Bioresorbable composite polymeric materials for tissue engineering applications

被引：33

作者：

Hajebi, Sakineh ^{[1
,2
]}

Nasr, SAeed Mohammadi ^{[3
]}

Rabiee, Navid ^{[4
]}

Bagherzadeh, Mojtaba ^{[4
]}

Ahmadi, Sepideh ^{[5
,6
]}

Rabiee, Mohammad ^{[7
]}

Tahriri, Mohammadreza ^{[8
]}

Tayebi, Lobat ^{[8
]}

Hamblin, Michael R. ^{[9
,10
,11
]}

机构：

[1] Sahand Univ Technol, Dept Polymer Engn, Tabriz, Iran

[2] Sahand Univ Technol, Inst Polymer Mat, Tabriz, Iran

[3] Sahand Univ Technol, Fac Chem Engn, Tabriz, Iran

[4] Sharif Univ Technol, Dept Chem, Tehran, Iran

[5] Shahid Beheshti Univ Med Sci, Sch Adv Technol Med, Dept Biotechnol, Student Res Comm, Tehran, Iran

[6] Shahid Beheshti Univ Med Sci, Cellular & Mol Biol Res Ctr, Tehran, Iran

[7] Amirkabir Univ Technol, Dept Biomed Engn, Biomat Grp, Tehran, Iran

[8] Marquette Univ, Sch Dent, Milwaukee, WI 53233 USA

[9] Massachusetts Gen Hosp, Wellman Ctr Photomed, Boston, MA 02114 USA

[10] Harvard Med Sch, Dept Dermatol, Boston, MA 02115 USA

[11] Univ Johannesburg, Fac Hlth Sci, Laser Res Ctr, Johannesburg, South Africa

来源：

INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS | 2021年 / 70卷 / 13期

关键词：

Biodegradable polymer; bioresorbable; tissue engineering; composite; IN-VITRO DEGRADATION; MECHANICAL-PROPERTIES; BIOMEDICAL APPLICATIONS; BIODEGRADABLE POLYMERS; PCL SCAFFOLDS; CURRENT STATE; BONE; HYDROXYAPATITE; FABRICATION; BLENDS;

D O I：

10.1080/00914037.2020.1765365

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

This review covers the development of bioresorbable polymeric composites for applications in tissue engineering. Various commercially available bioresobable polymers are described, with emphasis on recent bioresorbable composites based on natural and synthetic polymers. Bioresorbable polymers contain hydrolyzable bonds, which are subjected to chemical degradation via either reactive hydrolysis or enzyme-catalyzed active hydrolysis. For synthetic polymers, chemical hydrolysis is the most important mode of degradation. The degradation rate can be controlled by varying the molecular weight and crystallinity. Examples of bioresorbable polymers are: polyurethane, poly(D,L)lactide, poly(lactic-co-glycolic) acid, poly(alpha-hydroxy acids), cross-linked polyester hydrogels, poly(orthoesters), polyanhydrides and polyethylene glycol.

引用

页码：926 / 940

页数：15

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