Acinetobacter baumannii An emerging opportunistic pathogen

被引:587
作者
Howard, Aoife [1 ]
O'Donoghue, Michael [1 ]
Feeney, Audrey [1 ]
Sleator, Roy D. [1 ]
机构
[1] Cork Inst Technol, Dept Biol Sci, Cork, Ireland
关键词
Acinetobacter baumannii; pathogen; antibiotic; stress; virulence; infection; OXIDE RELEASING NANOPARTICLES; GRAM-NEGATIVE BACILLI; NITRIC-OXIDE; PHOTODYNAMIC THERAPY; POLYMYXIN-B; MULTIDRUG-RESISTANCE; NOSOCOMIAL PATHOGENS; RESTRICTION ANALYSIS; BETA-LACTAMASE; HUMAN SKIN;
D O I
10.4161/viru.19700
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Acinetobacter baumannii is an opportunistic bacterial pathogen primarily associated with hospital-acquired infections. The recent increase in incidence, largely associated with infected combat troops returning from conflict zones, coupled with a dramatic increase in the incidence of multidrug-resistant (MDR) strains, has significantly raised the profile of this emerging opportunistic pathogen. Herein, we provide an overview of the pathogen, discuss some of the major factors that have led to its clinical prominence and outline some of the novel therapeutic strategies currently in development.
引用
收藏
页码:243 / 250
页数:8
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