Pediatric Skull Base Meningiomas: Clinical Features and Surgical Outcomes

被引:3
作者
Li, Zhicen [1 ,2 ]
Li, Hao [1 ,2 ]
Wang, Shuo [1 ,2 ]
Zhao, Jizong [1 ,2 ]
Cao, Yong [1 ,2 ]
机构
[1] Capital Med Univ, Beijing Tiantan Hosp, Dept Neurosurg, 6 Tiantanxili, Beijing 100050, Peoples R China
[2] China Natl Clin Res Ctr Neurol Dis, Beijing, Peoples R China
关键词
pediatric meningiomas; skull base; clinical features; outcomes; SINGLE-CENTER EXPERIENCE; INTRACRANIAL MENINGIOMAS; MICROSURGICAL RESECTION; CHILDREN; MANAGEMENT; CHILDHOOD;
D O I
10.1177/0883073816664669
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The purpose of this study is to investigate the clinical, pathological, and prognostic characteristics of pediatric skull base meningiomas. A retrospective analysis of 44 pediatric skull base patients younger than 18 years who underwent surgery at Beijing Tiantan Hospital was performed. The study group included 20 males and 24 females. Multiple lesions were seen in 8 patients. WHO grade I was found in 28 patients and higher grade was seen in 16 patients. Recurrence or progression occurred in 10 patients after the initial operation. The overall survival rate in the follow-up period for the entire cohort was 89.7%. The authors found no sex predominance in pediatric skull base meningiomas. In addition, this lesion was more often seen in their second decades. In contrast to skull base meningiomas in adult patients, pediatric skull base meningiomas had a higher incidence of nonbenign histopathological variants and a higher rate of recurrence.
引用
收藏
页码:1523 / 1527
页数:5
相关论文
共 25 条
[1]   ABC Surgical Risk Scale for skull base meningioma: a new scoring system for predicting the extent of tumor removal and neurological outcome [J].
Adachi, Kazuhide ;
Kawase, Takeshi ;
Yoshida, Kazunari ;
Yazaki, Takahito ;
Onozuka, Satoshi .
JOURNAL OF NEUROSURGERY, 2009, 111 (05) :1053-1061
[2]   Pediatric intracranial meningiomas - Do they differ from their counterparts in adults? [J].
Arivazhagan, A. ;
Devi, B. Indira ;
Kolluri, Sastry V. R. ;
Abraham, R. G. ;
Sampath, S. ;
Chandramouli, B. A. .
PEDIATRIC NEUROSURGERY, 2008, 44 (01) :43-48
[3]   Surgical resection of pediatric skull base meningiomas [J].
Burkhardt, Jan-Karl ;
Neidert, Marian C. ;
Grotzer, Michael A. ;
Krayenbuehl, Niklaus ;
Bozinov, Oliver .
CHILDS NERVOUS SYSTEM, 2013, 29 (01) :83-87
[4]   Malignant potential of skull base versus non-skull base meningiomas: clinical series of 1,663 cases [J].
Cornelius, Jan Frederick ;
Slotty, Philipp Joerg ;
Steiger, Hans Jakob ;
Haenggi, Daniel ;
Polivka, Marc ;
George, Bernard .
ACTA NEUROCHIRURGICA, 2013, 155 (03) :407-413
[5]   CEREBRAL MENINGIOMAS IN CHILDREN [J].
FERRANTE, L ;
ACQUI, M ;
ARTICO, M ;
MASTRONARDI, L ;
ROCCHI, G ;
FORTUNA, A .
CHILDS NERVOUS SYSTEM, 1989, 5 (02) :83-86
[6]   Meningiomas of the Pediatric Skull Base: A Review [J].
Gump, William C. .
JOURNAL OF NEUROLOGICAL SURGERY PART B-SKULL BASE, 2015, 76 (01) :66-73
[7]   The role of radical microsurgical resection in multimodal treatment for skull base meningioma [J].
Ichinose, Tsutomu ;
Goto, Takeo ;
Ishibashi, Kenichi ;
Takami, Toshihiro ;
Ohata, Kenji .
JOURNAL OF NEUROSURGERY, 2010, 113 (05) :1072-1078
[8]   Meningiomas in children and adolescents: a meta-analysis of individual patient data [J].
Kotecha, Rishi S. ;
Pascoe, Elaine M. ;
Rushing, Elisabeth J. ;
Rorke-Adams, Lucy B. ;
Zwerdling, Ted ;
Gao, Xing ;
Li, Xin ;
Greene, Stephanie ;
Amirjamshidi, Abbas ;
Kim, Seung-Ki ;
Lima, Marco A. ;
Hung, Po-Cheng ;
Lakhdar, Faycal ;
Mehta, Nirav ;
Liu, Yuguang ;
Devi, B. Indira ;
Sudhir, B. Jayanand ;
Lund-Johansen, Morten ;
Gjerris, Flemming ;
Cole, Catherine H. ;
Gottardo, Nicholas G. .
LANCET ONCOLOGY, 2011, 12 (13) :1229-1239
[9]   Pediatric meningioma: current approaches and future direction [J].
Kotecha, Rishi S. ;
Junckerstorff, Reimar C. ;
Lee, Sharon ;
Cole, Catherine H. ;
Gottardo, Nicholas G. .
JOURNAL OF NEURO-ONCOLOGY, 2011, 104 (01) :1-10
[10]  
Lakhdar F, 2011, J NEUROSURG, V114, P1289