Vortex-Aligned Fullerene Nanowhiskers as a Scaffold for Orienting Cell Growth

被引：111

作者：

Krishnan, Venkata ^{[1
]}

Kasuya, Yuki ^{[2
]}

Ji, Qingmin ^{[1
]}

Sathish, Marappan ^{[1
]}

Shrestha, Lok Kumar ^{[1
]}

Ishihara, Shinsuke ^{[3
]}

Minami, Kosuke ^{[1
]}

Morita, Hiromi ^{[4
]}

Yamazaki, Tomohiko ^{[4
]}

Hanagata, Nobutaka ^{[4
]}

Miyazawa, Kun'ichi ^{[5
]}

Acharya, Somobrata ^{[6
]}

Nakanishi, Waka ^{[1
]}

Hill, Jonathan P. ^{[1
]}

Ariga, Katsuhiko ^{[1
]}

机构：

[1] Natl Inst Mat Sci, WPI Ctr Mat Nanoarchitecton MANA, Supermol Grp, Tsukuba, Ibaraki 3050044, Japan

[2] Tokyo Univ Sci, Dept Pure & Appl Chem, Noda, Chiba 2788510, Japan

[3] Natl Inst Mat Sci, Funct Geomat Grp, Tsukuba, Ibaraki 3050044, Japan

[4] Natl Inst Mat Sci, Nanotechnol Innovat Stn, Tsukuba, Ibaraki 3050047, Japan

[5] Natl Inst Mat Sci, Exploratory Nanotechnol Res Lab, Fullerene Engn Grp, Tsukuba, Ibaraki 3050044, Japan

[6] Indian Assoc Cultivat Sci, CAM, Kolkata 700032, India

来源：

ACS APPLIED MATERIALS & INTERFACES | 2015年 / 7卷 / 28期

基金：

日本科学技术振兴机构;

关键词：

fullerene C-60 nanowhiskers; vortex-flow-directed assembly; alignment of nanostructures; air-water interface; cell culture; C-60; NANORODS; NANOARCHITECTONICS; ASSEMBLIES; CRYSTALS; NANOSTRUCTURES; ARCHITECTURES; NANOSHEETS; NANOTUBES;

D O I：

10.1021/acsami.5b04811

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

A versatile method for the rapid fabrication of aligned fullerene C-60 nanowhiskers (C(60)NWs) at the airwater interface is presented. This method is based on the vortex motion of a subphase (water), which directs floating C(60)NWs to align on the water surface according to the direction of rotational flow. Aligned C(60)NWs could be transferred onto many different flat substrates, and, in this case, aligned C(60)NWs on glass substrates were employed as a scaffold for cell culture. Bone forming human osteoblast MG63 cells adhered well to the C(60)NWs, and their growth was found to be oriented with the axis of the aligned C(60)NWs. Cells grown on aligned C(60)NWs were more highly oriented with the axis of alignment than when grown on randomly oriented nanowhiskers. A study of cell proliferation on the C(60)NWs revealed their low toxicity, indicating their potential for use in biomedical applications.

引用

页码：15667 / 15673

页数：7

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