Biotransformation of (-)-caryophyllene oxide by cell suspension culture of Catharanthus roseus

被引：15
|
作者：
Choudhary, MI [1 ]
Siddiqui, ZA [1 ]
Khan, S [1 ]
Saifullah [1 ]
Musharraf, SG [1 ]
Atta-ur-Rahman [1 ]
机构：
[1] Univ Karachi, HEJ Res Inst Chem, Int Ctr Chem Sci, Karachi 75270, Pakistan
来源：
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES | 2006年 / 61卷 / 02期
关键词：
(-)-caryophyllene oxide; biotransformation; Catharanthus roseus; cell suspension cultures;
D O I：
10.1515/znb-2006-0214
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Catharanthus roseus cell suspension cultures were employed for the biotransformation of (-)-caryophyllene oxide (1), and four metabolites, 15-hydroxycaryophyllene oxide (2), 4 beta,5 alpha-dihydroxycaryophyll-8(13)-ene (3), 2 beta-hydroxycaryophyllene oxide (4), and 2-hydroxy-4,5-epoxycaryophyllan-13-ol (5) were obtained. Metabolites 4 and 5 were found to be new compounds, and their structures were deduced by different spectroscopic techniques.
引用
收藏
页码：197 / 200
页数：4
相关论文
共 50 条
  • [31] Vindoline biosynthesis is transcriptionally blocked in Catharanthus roseus cell suspension cultures
    Vázquez-Flota, F
    De Luca, V
    Carrillo-Pech, M
    Canto-Flick, A
    Miranda-Ham, MD
    MOLECULAR BIOTECHNOLOGY, 2002, 22 (01) : 1 - 8
  • [32] Effect of nitric oxide on catharanthine production and growth of Catharanthus roseus suspension cells
    Xu, MJ
    Dong, JF
    Zhu, MY
    BIOTECHNOLOGY AND BIOENGINEERING, 2005, 89 (03) : 367 - 371
  • [33] Physiological and ultrastructural responses of Catharanthus roseus cell suspension to salt stress
    S. Elkahoui
    Z. Barhoumi
    N. Djébali
    W. Djébali
    W. Chaïbi
    F. Limam
    A. Smaoui
    Russian Journal of Plant Physiology, 2013, 60 : 244 - 249
  • [34] Alkaloid accumulation in Catharanthus roseus cell suspension cultures fed with stemmadenine
    El-Sayed, M
    Choi, YH
    Frédérich, M
    Roytrakul, S
    Verpoorte, R
    BIOTECHNOLOGY LETTERS, 2004, 26 (10) : 793 - 798
  • [35] Impact of hypoxia on the growth and alkaloid accumulation in Catharanthus roseus cell suspension
    Senoussi, Mohammed Mourad
    Nora, Bassa
    Joel, Creche
    ACTA PHYSIOLOGIAE PLANTARUM, 2009, 31 (02) : 359 - 362
  • [36] Biotransformation of phenolic compounds by the cultured cells of Catharanthus roseus
    Shimoda, K
    Yamane, S
    Hirakawa, H
    Ohta, S
    Hirata, T
    JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 2002, 16 (5-6) : 275 - 281
  • [37] Vinblastine synthesis under the influence of CaCl2 elicitation in embryogenic cell suspension culture of Catharanthus roseus
    Siddiqui, Zahid Hameed
    Mujib, Abdul
    Abbas, Zahid Khorshid
    Noorani, M. Salik
    Khan, Salim
    SOUTH AFRICAN JOURNAL OF BOTANY, 2023, 154 : 319 - 329
  • [38] SYNCHRONY INDUCED BY DOUBLE PHOSPHATE STARVATION IN A SUSPENSION-CULTURE OF CATHARANTHUS-ROSEUS
    AMINO, S
    FUJIMURA, T
    KOMAMINE, A
    PHYSIOLOGIA PLANTARUM, 1983, 59 (03) : 393 - 396
  • [39] Biotransformation of 2α,5α,10β,14β-tetraacetoxy-4(20), 11-taxadiene by cell suspension cultures of Catharanthus roseus
    Dai, JU
    Cui, J
    Zhu, WH
    Guo, HZ
    Ye, M
    Hu, Q
    Zhang, DY
    Zheng, JH
    Guo, D
    PLANTA MEDICA, 2002, 68 (12) : 1113 - 1117
  • [40] INDOLE ALKALOIDS FROM CELL-SUSPENSION CULTURES OF CATHARANTHUS-ROSEUS AND CATHARANTHUS-OVALIS
    STOCKIGT, J
    SOLL, HJ
    PLANTA MEDICA, 1980, 40 (01) : 22 - 30
12345