Biotransformation of (-)-caryophyllene oxide by cell suspension culture of Catharanthus roseus

被引：15
|
作者：
Choudhary, MI [1 ]
Siddiqui, ZA [1 ]
Khan, S [1 ]
Saifullah [1 ]
Musharraf, SG [1 ]
Atta-ur-Rahman [1 ]
机构：
[1] Univ Karachi, HEJ Res Inst Chem, Int Ctr Chem Sci, Karachi 75270, Pakistan
来源：
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES | 2006年 / 61卷 / 02期
关键词：
(-)-caryophyllene oxide; biotransformation; Catharanthus roseus; cell suspension cultures;
D O I：
10.1515/znb-2006-0214
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Catharanthus roseus cell suspension cultures were employed for the biotransformation of (-)-caryophyllene oxide (1), and four metabolites, 15-hydroxycaryophyllene oxide (2), 4 beta,5 alpha-dihydroxycaryophyll-8(13)-ene (3), 2 beta-hydroxycaryophyllene oxide (4), and 2-hydroxy-4,5-epoxycaryophyllan-13-ol (5) were obtained. Metabolites 4 and 5 were found to be new compounds, and their structures were deduced by different spectroscopic techniques.
引用
收藏
页码：197 / 200
页数：4
相关论文
共 50 条
  • [21] Regulation of vinblastine biosynthesis in cell suspension cultures of catharanthus roseus
    Guo, Zhi-Gang
    Liu, Yun
    Gong, Mei-Zhen
    Chen, Wen
    Li, Wen-Yuan
    PLANT CELL TISSUE AND ORGAN CULTURE, 2013, 112 (01) : 43 - 54
  • [22] Regulation of vinblastine biosynthesis in cell suspension cultures of catharanthus roseus
    Zhi-Gang Guo
    Yun Liu
    Mei-Zhen Gong
    Wen Chen
    Wen-Yuan Li
    Plant Cell, Tissue and Organ Culture (PCTOC), 2013, 112 : 43 - 54
  • [23] The effect of the aggregate size on the production of ajmalicine and tryptamine in Catharanthus roseus suspension culture
    Kessler, M
    ten Hoopen, HJG
    Furusaki, S
    ENZYME AND MICROBIAL TECHNOLOGY, 1999, 24 (5-6) : 308 - 315
  • [24] Effects of some heavy metals on cell suspension cultures of Catharanthus roseus
    Zhu Lizhong (Department of Environmental Science)
    Journal of Environmental Sciences, 1995, (01) : 60 - 65
  • [25] Impact of hypoxia on the growth and alkaloid accumulation in Catharanthus roseus cell suspension
    Mohammed Mourad Senoussi
    Bassa Nora
    Crèche Joêl
    Acta Physiologiae Plantarum, 2009, 31 : 359 - 362
  • [26] Vindoline biosynthesis is transcriptionally blocked in Catharanthus roseus cell suspension cultures
    Felipe Vázquez-Flota
    Vincenzo De Luca
    Mildred Carrillo-Pech
    Adriana Canto-Flick
    María de Lourdes Miranda-Ham
    Molecular Biotechnology, 2002, 22 : 1 - 8
  • [27] ALKALOID PRODUCTION BY CELL-SUSPENSION CULTURES OF CATHARANTHUS-ROSEUS
    VINAS, R
    PAREILLEUX, A
    PHYSIOLOGIE VEGETALE, 1982, 20 (02): : 219 - 225
  • [28] Alkaloid accumulation in Catharanthus roseus cell suspension cultures fed with stemmadenine
    Magdi El-Sayed
    Young H. Choi
    M. Frédérich
    Sittiruk Roytrakul
    Rob Verpoorte
    Biotechnology Letters, 2004, 26 : 793 - 798
  • [29] Physiological and ultrastructural responses of Catharanthus roseus cell suspension to salt stress
    Elkahoui, S.
    Barhoumi, Z.
    Djebali, N.
    Djebali, W.
    Chaibi, W.
    Limam, F.
    Smaoui, A.
    RUSSIAN JOURNAL OF PLANT PHYSIOLOGY, 2013, 60 (02) : 244 - 249
  • [30] HYDROXYLATION OF PIPERITONE BY CELL-SUSPENSION CULTURES OF CATHARANTHUS-ROSEUS
    HAMADA, H
    FUCHIKAMI, Y
    IKEMATSU, Y
    HIRATA, T
    WILLIAMS, HJ
    SCOTT, AI
    PHYTOCHEMISTRY, 1994, 37 (04) : 1037 - 1038
12345