Biotransformation of (-)-caryophyllene oxide by cell suspension culture of Catharanthus roseus

被引：15
|
作者：
Choudhary, MI [1 ]
Siddiqui, ZA [1 ]
Khan, S [1 ]
Saifullah [1 ]
Musharraf, SG [1 ]
Atta-ur-Rahman [1 ]
机构：
[1] Univ Karachi, HEJ Res Inst Chem, Int Ctr Chem Sci, Karachi 75270, Pakistan
来源：
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES | 2006年 / 61卷 / 02期
关键词：
(-)-caryophyllene oxide; biotransformation; Catharanthus roseus; cell suspension cultures;
D O I：
10.1515/znb-2006-0214
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Catharanthus roseus cell suspension cultures were employed for the biotransformation of (-)-caryophyllene oxide (1), and four metabolites, 15-hydroxycaryophyllene oxide (2), 4 beta,5 alpha-dihydroxycaryophyll-8(13)-ene (3), 2 beta-hydroxycaryophyllene oxide (4), and 2-hydroxy-4,5-epoxycaryophyllan-13-ol (5) were obtained. Metabolites 4 and 5 were found to be new compounds, and their structures were deduced by different spectroscopic techniques.
引用
收藏
页码：197 / 200
页数：4
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