Sepsis and Septic Shock

被引：25

作者：

Maloney, Patrick J. ^{[1
]}

机构：

[1] Univ Colorado, Sch Med, Dept Emergency Med, Denver Hlth Med Ctr, Denver, CO 80204 USA

来源：

EMERGENCY MEDICINE CLINICS OF NORTH AMERICA | 2013年 / 31卷 / 03期

关键词：

Systemic inflammatory response syndrome (SIRS); Sepsis; Septic shock; Early goal-directed therapy; Vasopressors; Children; C-REACTIVE PROTEIN; EARLY LACTATE CLEARANCE; BACTERIAL-INFECTION; HEMODYNAMIC SUPPORT; FLUID RESUSCITATION; AMERICAN-COLLEGE; CHILDREN; EPIDEMIOLOGY; BACTEREMIA; MORTALITY;

D O I：

10.1016/j.emc.2013.04.006

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Early recognition of sepsis and septic shock in children relies on obtaining an attentive clinical history, accurate vital signs, and a physical examination focused on mental status, work of breathing, and circulatory status. Laboratory tests may support the diagnosis but are not reliable in isolation. The goal of septic shock management is reversal of tissue hypoperfusion. The therapeutic end point is shock reversal. Mortality is significantly better among children when managed appropriately. Every physician who cares for children must strive to have a high level of suspicion and keen clinical acumen for recognizing the rare but potentially seriously ill child.

引用

页码：583 / +

页数：19

共 49 条

[1]

American Academy of Pediatrics, 2005, PED ED PREH PROF PEP

[2]

American Academy of Pediatrics American College of Emergency Physicians, 2011, APLS ADV PED LIF SUP

[3] Progress toward eliminating Haemophilus influenzae type b disease among infants and children -: United States, 1987-1997 [J].

不详 .

ANNALS OF EMERGENCY MEDICINE, 1999, 34 (01) :109-110

[4]

[Anonymous], 2008, INTENS CARE MED, DOI [DOI 10.1007/s00134-007-0934-2, DOI 10.1007/s00134-008-1040-9]

[5] MULTICENTER STUDY OF EARLY LACTATE CLEARANCE AS A DETERMINANT OF SURVIVAL IN PATIENTS WITH PRESUMED SEPSIS [J].

Arnold, Ryan C. ;

Shapiro, Nathan I. ;

Jones, Alan E. ;

Schorr, Christa ;

Pope, Jennifer ;

Casner, Elisabeth ;

Parrillo, Joseph E. ;

Dellinger, R. Phillip ;

Trzeciak, Stephen .

SHOCK, 2009, 32 (01) :35-39

[6]

Atkins DL, 2006, PEDIATRICS, V117, pE989

[7] Global, regional, and national causes of child mortality in 2008: a systematic analysis [J].

Black, Robert E. ;

Cousens, Simon ;

Johnson, Hope L. ;

Lawn, Joy E. ;

Rudan, Igor ;

Bassani, Diego G. ;

Jha, Prabhat ;

Campbell, Harry ;

Walker, Christa Fischer ;

Cibulskis, Richard ;

Eisele, Thomas ;

Liu, Li ;

Mathers, Colin .

LANCET, 2010, 375 (9730) :1969-1987

[8] DEFINITIONS FOR SEPSIS AND ORGAN FAILURE [J].

BONE, RC ;

SPRUNG, CL ;

SIBBALD, WJ .

CRITICAL CARE MEDICINE, 1992, 20 (06) :724-726

[9] Clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock: 2007 update from the American College of Critical Care Medicine [J].

Brierley, Joe ;

Carcillo, Joseph A. ;

Choong, Karen ;

Cornell, Tim ;

DeCaen, Allan ;

Deymann, Andreas ;

Doctor, Allan ;

Davis, Alan ;

Duff, John ;

Dugas, Marc-Andre ;

Duncan, Alan ;

Evans, Barry ;

Feldman, Jonathan ;

Felmet, Kathryn ;

Fisher, Gene ;

Frankel, Lorry ;

Jeffries, Howard ;

Greenwald, Bruce ;

Gutierrez, Juan ;

Hall, Mark ;

Han, Yong Y. ;

Hanson, James ;

Hazelzet, Jan ;

Hernan, Lynn ;

Kiff, Jane ;

Kissoon, Niranjan ;

Kon, Alexander ;

Irazusta, Jose ;

Lin, John ;

Lorts, Angie ;

Mariscalco, Michelle ;

Mehta, Renuka ;

Nadel, Simon ;

Nguyen, Trung ;

Nicholson, Carol ;

Peters, Mark ;

Okhuysen-Cawley, Regina ;

Poulton, Tom ;

Relves, Monica ;

Rodriguez, Agustin ;

Rozenfeld, Ranna ;

Schnitzler, Eduardo ;

Shanley, Tom ;

Skache, Sara ;

Skippen, Peter ;

Torres, Adalberto ;

von Dessauer, Bettina ;

Weingarten, Jacki ;

Yeh, Timothy ;

Zaritsky, Arno .

CRITICAL CARE MEDICINE, 2009, 37 (02) :666-688

[10] ROLE OF EARLY FLUID RESUSCITATION IN PEDIATRIC SEPTIC SHOCK [J].

CARCILLO, JA ;

DAVIS, AL ;

ZARITSKY, A .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1991, 266 (09) :1242-1245

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