An efficient FeCl3/SiO2 NPs as a reusable heterogeneous catalyzed five-component reactions of tetrahydropyridines under mild conditions

被引：24

作者：

Safaei-Ghomi, Javad ^{[1
]}

Ziarati, Abolfazl ^{[1
]}

机构：

[1] Univ Kashan, Fac Chem, Dept Organ Chem, Kashan 51167, Iran

来源：

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY | 2013年 / 10卷 / 01期

关键词：

Tetrahydropyridines; Five-component; Nano silica; Reusable catalyst; One pot; ONE-POT SYNTHESIS; DIELS-ALDER REACTION; MULTICOMPONENT REACTIONS; ASYMMETRIC-SYNTHESIS; CONCISE SYNTHESIS; DERIVATIVES; PIPERIDINES; ATOM;

D O I：

10.1007/s13738-012-0134-z

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A convenient, simple, and multicomponent coupling strategy has been developed for the synthesis of highly functionalized tetrahydropyridines using FeCl3/SiO2 NPs as catalyst. This method demonstrated five-component coupling reactions of 1,3-dicarbonyl compounds, aromatic aldehydes and amines without an inert atmosphere. Atom economy, good yields, environmentally benign, and mild reaction conditions are some of the important features of this protocol. Notably, this catalyst could be recycled and reused for several times without noticeably decreasing the catalytic activity.

引用

页码：135 / 139

页数：5

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