Tamoxifen Use in Postmenopausal Breast Cancer: CYP2D6 Matters

被引:85
作者
Brauch, Hiltrud [1 ,2 ]
Schroth, Werner [1 ,2 ]
Goetz, Matthew P. [3 ]
Muerdter, Thomas E. [1 ,2 ]
Winter, Stefan [1 ,2 ]
Ingle, James N. [3 ]
Schwab, Matthias [1 ,2 ,4 ]
Eichelbaum, Michel [1 ,2 ]
机构
[1] Dr Margarete Fischer Bosch Inst Clin Pharmacol, Stuttgart, Germany
[2] Univ Tubingen, Tubingen, Germany
[3] Mayo Clin, Rochester, MN USA
[4] Univ Tubingen Hosp, Inst Expt & Clin Pharmacol & Toxicol, Tubingen, Germany
关键词
GROUP; 1-98; TRIAL; METABOLITE PLASMA-CONCENTRATIONS; REUPTAKE INHIBITOR PAROXETINE; ESTROGEN-RECEPTOR; ACTIVE METABOLITE; RE CYP2D6; ADJUVANT TAMOXIFEN; UGT2B7; GENOTYPE; WOMEN; POLYMORPHISMS;
D O I
10.1200/JCO.2012.44.6625
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:176 / 180
页数:5
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