A NOVEL AND SENSITIVE DETECTION METHOD OF HYDROGEN PEROXIDE AND GLUCOSE BASED ON COPPER NANOCLUSTERS

被引：0
|
作者：
Zhou, Shuqi [1 ]
Wang, Xinyi [1 ]
Kong, Liubing [1 ]
Lin, Wencheng [1 ]
Ma, Chiyu [1 ]
Sun, Xianyou [1 ]
Huang, Zhuoru [1 ]
Ying, Kejing [2 ]
Wan, Hao [1 ,3 ,4 ]
Wang, Ping [1 ,3 ,4 ]
机构：
[1] Zhejiang Univ, Dept Biomed Engn, Biosensor Natl Special Lab, Key Lab Biomed Engn,Educ Minist, Hangzhou 310027, Peoples R China
[2] Zhejiang Univ, Sir Run Run Shaw Hosp, Dept Resp Dis, Hangzhou 310016, Peoples R China
[3] Chinese Acad Sci, State Key Lab Transducer Technol, Shanghai 200050, Peoples R China
[4] Zhejiang Univ, Canc Ctr, Hangzhou 310058, Zhejiang, Peoples R China
来源：
2022 IEEE INTERNATIONAL SYMPOSIUM ON OLFACTION AND ELECTRONIC NOSE (ISOEN 2022) | 2022年
基金：
中国国家自然科学基金; 中国博士后科学基金;
关键词：
copper nanocluster; colorimetric; hydrogen peroxide; glucose;
D O I：
10.1109/ISOEN54820.2022.9789649
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The level of glucose in blood or urine are an important indicator of diabetes. Here, a sensitive and easily operated colorimetric methods was established based on the mercaptosuccinic acid modified copper nanocluster(MSA-CuNCs). MSA-CuNCs, which was act as both thehydrogen peroxide catalyst and the chromogenic reagent. By observing the absorption at 520 nm, the H2O2 could be detected, with the detection range of 0.2-5 mM and the detection limit of 0.05 mM. Using glucose oxidase, the glucose could also be detected, the detection range was 0.2-5 mM with the detection limit of 0.12 mM. This simple and cost-effective approach indicating its great potential for point-of-care applications
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页数：3
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