Lipoprotein lipase activity of post-heparin plasma in Japanese place cattle affected with fat necrosis

被引：5

作者：

Katamoto, H ^{[1
]}

Aoki, M ^{[1
]}

Shimada, Y ^{[1
]}

Hakogi, E ^{[1
]}

机构：

[1] WADAYAMA LIVESTOCK HYG SERV CTR,WADAYAMA,HYOGO 66952,JAPAN

来源：

BRITISH VETERINARY JOURNAL | 1996年 / 152卷 / 03期

关键词：

heparin; lipoprotein lipase; isoprothiolane; fat necrosis; cattle;

D O I：

10.1016/S0007-1935(96)80106-0

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Post-heparin plasma (PHP) lipoprotein lipase (LPL) activity and serum lipoprotein concentration were examined in Japanese Black cows affected with fat necrosis. The PHP-LPL activity in the affected cows tvas significantly (P<0.001) higher than in normal animals and tended to reduce 4 weeks after treatment with isoprothiolane. This finding indicates that affected cows have a predisposition to deposit more fat into adipose tissue than normal animals. The serum concentrations of triglyceride in beta-lipoprotein and of cholesterol, phospholipid and total lipid in alpha-lipoprotein were significantly (P<0.05) lower in the affected cows. Elevated levels of phospholipid and total lipid in alpha-lipoprotein as well as decreased levels of non-esterified fatty acid (NEFA) were observed after medication. It is suggested that isoprothiolane produces an improvement in hepatic lipid metabolism including acceleration of plasma NEFA uptake and alpha-lipoprotein secretion in affected cows.

引用

页码：339 / 345

页数：7

共 14 条

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