Unpicking neurodegeneration in a dish with human pluripotent stem cells One cell type at a time

被引:2
作者
Bilican, Bilada [1 ,2 ]
Serio, Andrea [1 ,2 ]
Shaw, Christopher E. [3 ]
Maniatis, Tom [4 ]
Chandran, Siddharthan [1 ,2 ]
机构
[1] Univ Edinburgh, Euan MacDonald Ctr Motor Neurone Dis Res, Ctr Neuroregenerat, Edinburgh, Midlothian, Scotland
[2] Univ Edinburgh, Med Res Council Ctr Regenerat Med, Edinburgh, Midlothian, Scotland
[3] Kings Coll London, Inst Psychiat, Ctr Neurodegenerat Res, London WC2R 2LS, England
[4] Columbia Univ, Dept Biochem & Mol Biophys, New York, NY USA
基金
英国医学研究理事会; 英国惠康基金;
关键词
ALS; astrocytes; stem cell; reactive gliosis; glia; TDP-43; SOD1; disease modeling; MOTOR-NEURONS; ASTROCYTES; MODEL; ALS;
D O I
10.4161/cc.25705
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:2339 / 2340
页数:2
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