Serum lipoprotein (a) in diabetic patients with various renal function not yet on dialysis

被引：23

作者：

Baradaran, Azar ^{[1
]}

Madihi, Yahya ^{[2
]}

Merrikhi, Alireza ^{[2
]}

Rafieian-Kopaei, Mahmoud ^{[3
]}

Nasri, Hamid ^{[4
]}

机构：

[1] Isfahan Univ Med Sci, Dept Pathol, Esfahan, Iran

[2] Isfahan Univ Med Sci, Child Growth & Dev Res Ctr, Esfahan, Iran

[3] Shahrekord Univ Med Sci, Med Plants Res Ctr, Shahrekord, Iran

[4] Shahrekord Univ Med Sci, Shahrekord, Iran

来源：

PAKISTAN JOURNAL OF MEDICAL SCIENCES | 2013年 / 29卷

关键词：

Lipoprotein(a); Diabetes mellitus; Creatinine clearance; CORONARY HEART-DISEASE; APOLIPOPROTEIN(A) PHENOTYPES; NIDDM PATIENTS; ASSOCIATION; ATHEROSCLEROSIS; PLASMA; LIPIDS; RISK; MELLITUS; TRIAL;

D O I：

10.12669/pjms.291(Suppl).3533

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

To examine the association of serum serum lipoprotein(a)[Lp(a)] concentration with various demographic and biochemical indexes of diabetic patients, we conducted a study on type 2 diabetes mellitus(T2D) patients. Patients were under treatment with insulin injection or oral hypoglycemic agents with various creatinine clearances not yet on dialysis. We studied 122 patients, with a mean age of 63 +/- 10 years. The duration of diabetes was 7.4 +/- 5.8 years. In this cross-sectional study, serum Lp(a), HbA(1c), body mass index (BMI) and creatinine clearance were assessed. The mean serum Lp(a) was 22.2 +/- 24.7 mg/dL(median: 18.3 mg/dL), and serum Lp(a) levels more than 30 mg/dL was found in 29(23.8%) patients. A significant inverse correlation of serum Lp(a) with clearance of creatinine was observed. This study suggests that renal function is an independent determinant of serum Lp(a) in diabetic patients.

引用

页码：354 / 357

页数：4

共 54 条

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