Pharmacologic Profile of SCH 530348, a Novel Oral Antiplatelet Agent Selective for the Protease-Activated Receptor-1 (PAR-1)

被引：0
|
作者：
Chintala, Madhu [1 ]
Ahn, Ho-Sam [1 ]
Foster, Carolyn [1 ]
Agans, Jacqueline [1 ]
Boykow, George [1 ]
机构：
[1] Schering Plough Rsch Inst, Kenilworth, NJ USA
来源：
CIRCULATION | 2008年 / 118卷 / 18期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：S374 / S374
页数：1
相关论文
共 50 条
  • [31] IN VIVO PROTEASE-ACTIVATED RECEPTOR-1 MEDIATED CORONARY VASOREACTIVITY CORRELATES WITH PAR-1 EXPRESSION DISTRIBUTION IN THE CORONARY VASCULAR WALL
    Kasasbeh, E. S.
    Phillips, S. A.
    Couhtino, L.
    Williams, P.
    Nunnally, A. H.
    Adcock, J.
    Wang, L.
    Hamm, H. E.
    Cleator, J. H.
    CARDIOLOGY, 2015, 131 : 285 - 285
  • [32] Expression of protease-activated receptor-1 (PAR-1): A differential marker for metastasis of squamous cell carcinoma of the head and neck (SCCHN)
    Zhang, X
    Hunt, JL
    Landsittel, DP
    Shin, DM
    Chen, ZG
    CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2003, 12 (11) : 1309S - 1309S
  • [33] The Effect of Protease-Activated Receptor-1 (PAR-1) Inhibition on Endothelial-Related Biomarkers in Patients with Coronary Artery Disease
    Nilsen, Dennis W. T.
    Roysland, Michelle
    Ueland, Thor
    Aukrust, Pal
    Michelsen, Annika E.
    Staines, Harry
    Barvik, Stale
    Kontny, Frederic
    Nordrehaug, Jan Erik
    Bonarjee, Vernon V. S.
    THROMBOSIS AND HAEMOSTASIS, 2023, 123 (05) : 510 - 521
  • [34] SCH-530348, a thrombin receptor (PAR-1) antagonist for the prevention and treatment of atherothrombosis
    Oestreich, Julie
    CURRENT OPINION IN INVESTIGATIONAL DRUGS, 2009, 10 (09) : 988 - 996
  • [35] Protease-Activated Receptor 1 (PAR-1) Antagonists as Potential Treatment for Acute Coronary Syndrome
    Abdel-Magid, Ahmed F.
    ACS MEDICINAL CHEMISTRY LETTERS, 2016, 7 (10): : 881 - 883
  • [36] Autoimmune Targeting of Protease Activated Receptor-1 (PAR-1) Deregulates VEGF and Disturbs Neoangiogenesis
    Catar, R.
    Schramm, I.
    Simon, M.
    Wischnewski, O.
    Philippe, A.
    Kusch, A.
    Dragun, D.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2014, 14 : 382 - 382
  • [37] AUTOIMMUNE TARGETING OF PROTEASE ACTIVATED RECEPTOR-1 (PAR-1) DEREGULATES VEGF AND DISTURBS NEOANGIOGENESIS
    Schramm, I.
    Catar, R.
    Simon, M.
    Wischnewski, O.
    Philippe, A.
    Kusch, A.
    Dragun, D.
    TRANSPLANT INTERNATIONAL, 2013, 26 : 24 - 24
  • [38] Protease activated receptor-1 (PAR-1) mediated platelet aggregation is dependant on clopidogrel response
    Kreutz, Rolf P.
    Breall, Jeffrey A.
    Kreutz, Yvonne
    Owens, Janelle
    Lu, Deshun
    Bolad, Islam
    von der Lohe, Elisabeth
    Sinha, Anjan
    Flockhart, David A.
    THROMBOSIS RESEARCH, 2012, 130 (02) : 198 - 202
  • [39] Protease Activated Receptor-1 (PAR-1) Mediated Platelet Aggregation is Dependant on Clopidogrel Response
    Kreutz, Rolf P.
    Flockhart, David A.
    Kreutz, Yvonne
    Breall, Jeffrey A.
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2011, 58 (20) : B44 - B44
  • [40] Effect of Protease-Activated Receptor-1 (PAR-1) Activating Peptide in Murine Model of Endotoxin-Induced Lung Injury.
    Tanaka, R.
    Goto, E.
    Tsumura, S.
    Kojima, K.
    Saeki, S.
    Ito, K.
    Saita, N.
    Kohrogi, H.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2009, 179
12345