Two new oleanane-type saponins from the husks of Xanthoceras sorbifolia Bunge

被引:11
作者
Li, Ying-Ying [1 ]
Xiang, Zheng [1 ]
Cui, Hao [1 ]
Xiao, Hang [1 ]
Kang, Ting-Guo [1 ]
Dou, De-Qiang [1 ]
Kuang, Hai-Xue [2 ]
机构
[1] Liaoning Univ Tradit Chinese Med, Coll Pharm, Dalian 116600, Peoples R China
[2] Heilongjiang Univ Tradit Chinese Med, Harbin 150040, Peoples R China
关键词
saponin; cytotoxicity; Xanthoceras sorbifolia Bunge; PROSAPOGENINS; TRITERPENOIDS; CARPOPHORE;
D O I
10.1080/14786419.2012.666748
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Two new oleanane-type pentacyclic triterpenoid saponins were isolated from the husks of Xanthoceras sorbifolia Bunge and their structures were elucidated as 3-O-beta-D-glucopyranosyl (1???6)-beta-D-glucopyranosyl-28-O-a-L-rhamnopyranosyl (1???2) [beta-D-glucopyranosyl (1???6)] beta-D-glucopyranosyl-21 beta,22a-dihydroxyl-olean-12,15-diene and 3-O-beta-D-glucopyranosyl (1???2)-beta-D-glucopyranosyl-28-O-a-L-rhamnopyranosyl (1???2) [beta-D-glucopyranosyl (1???6)] beta-D-glucopyranosy-21 beta,22a-dihydroxyl-olean-12-ene. Meanwhile, the cytotoxic activities of these two compounds were tested on human gastric cancer cell (SGC-7901) and hepatoma carcinoma cell (HepG-2).
引用
收藏
页码:208 / 214
页数:7
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