Scandium triflate-catalyzed one-pot multi-component synthesis of 2-amino-6-thiopyridine-3,5-dicarbonitriles

被引：12

作者：

Kottawar, Shrinivas S. ^{[1
]}

Siddiqui, Shapi A. ^{[1
]}

Bhusare, Sudhakar R. ^{[1
]}

机构：

[1] Dnyanopasak Coll, Dept Chem, Parbhani 431401, Maharashtra, India

来源：

HETEROCYCLIC COMMUNICATIONS | 2012年 / 18卷 / 5-6期

关键词：

aldehydes; 2-amino-6-thiopyridine-3,5-dicarbonitrile; malononitrile; multi-component reaction; scandium triflate; thiophenol; HIGHLY SUBSTITUTED PYRIDINES; 3-COMPONENT SYNTHESIS; 1,4-DIHYDROPYRIDINES; ADENOSINE;

D O I：

10.1515/hc-2012-0103

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Scandium triflate efficiently promotes a one-pot, three-component condensation of aldehydes, malononitrile, and thiophenols to produce highly substituted pyridines in good yields. This reaction does not involve any hazardous organic solvent and toxic catalyst.

引用

页码：249 / 252

页数：4

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