Association of Anxiety-Related Polymorphisms with Sports Performance in Chilean Long Distance Triathletes: A Pilot Study

被引：0
作者：
Sanhueza, Jorge A. [1 ]
Zambrano, Tomas [1 ]
Bahamondes-Avila, Carlos [2 ]
Salazar, Luis A. [1 ,3 ]
机构：
[1] Univ La Frontera, Ctr Mol Biol & Pharmacogenet Sci & Technol Biores, Temuco, Chile
[2] Univ Mayor, Sch Med, Temuco, Chile
[3] Univ La Frontera, Millennium Inst Res Depress & Personal MIDAP, Temuco, Chile
来源：
Journal of Sports Science and Medicine | 2016年 / 15卷 / 04期
关键词：
Sports performance; polymorphisms; genetics; anxiety disorders; ACE I/D POLYMORPHISM; RECEPTOR GENE POLYMORPHISM; SEROTONIN TRANSPORTER; PHYSICAL PERFORMANCE; ENDURANCE PERFORMANCE; IRONMAN TRIATHLON; MAJOR DEPRESSION; DISORDER; STRESS; MECHANISMS;
D O I：
暂无
中图分类号：
G8 [体育];
学科分类号：
04 ; 0403 ;
摘要：
Different factors affecting athletic performance are well established: intensity and type of training, anthropometric characteristics as well as an important psychological component. However, the contribution of the genetic background has been less investigated. The aim of the present study was to investigate the influence of polymorphisms within genes associated with stress and anxiety (5HTT, CRH2R, ACE, NK1R, 5HT1AR and CRFBP) on the physical capability and sports performance in triathletes. One hundred and ninety two (192) unrelated Chilean triathletes who participated in the 2014 70.3 Pucon city triathlon were divided into opposite subgroups of sports performance according to their time results. We identified significant associations for five polymorphisms (5HTT 5- HTTLPR, ACE I/ D, NK1R rs6715729, 5HT1AR - 1019C>G and CRF-BP CRFBPs11) with athletic performance. Our results indicate that these polymorphisms are associated with differential sports performance in Chilean triathletes, establishing an initial background for better understanding the relationship between physical performance, genetics and anxiety disorders.
引用
收藏
页码：554 / 561
页数：8
相关论文
共 44 条
  • [1] Angiotensin-converting enzyme gene variants are associated with both cortisol secretion and late-life depression
    Ancelin, M-L
    Carriere, I.
    Scali, J.
    Ritchie, K.
    Chaudieu, I.
    Ryan, J.
    [J]. TRANSLATIONAL PSYCHIATRY, 2013, 3 : e322 - e322
  • [2] The role of corticotropin-releasing factor receptors in stress and anxiety
    Bale, TL
    Lee, KF
    Vale, WW
    [J]. INTEGRATIVE AND COMPARATIVE BIOLOGY, 2002, 42 (03) : 552 - 555
  • [3] Effect of 5-HT1A-receptor functional polymorphism on Theory of Mind performances in schizophrenia
    Bosia, Marta
    Anselmetti, Simona
    Bechi, Margherita
    Lorenzi, Cristina
    Pirovano, Adele
    Cocchi, Federica
    Buonocore, Mariachiara
    Bramanti, Placido
    Smeraldi, Enrico
    Cavallaro, Roberto
    [J]. PSYCHIATRY RESEARCH, 2011, 188 (02) : 187 - 190
  • [4] Association between the ACE I/D gene polymorphism and physical performance in a homogeneous non-elite cohort
    Cam, FS
    Colakoglu, M
    Sekuri, C
    Colakoglu, S
    Sahan, C
    Berdeli, A
    [J]. CANADIAN JOURNAL OF APPLIED PHYSIOLOGY-REVUE CANADIENNE DE PHYSIOLOGIE APPLIQUEE, 2005, 30 (01): : 74 - 86
  • [5] The interleukin-6, serotonin transporter, and monoamine oxidase A genes and endurance performance during the South African Ironman Triathlon
    de Milander, Liesl
    Stein, Dan J.
    Collins, Malcolm
    [J]. APPLIED PHYSIOLOGY NUTRITION AND METABOLISM, 2009, 34 (05) : 858 - 865
  • [6] Compression stockings do not improve muscular performance during a half-ironman triathlon race
    Del Coso, Juan
    Areces, Francisco
    Jose Salinero, Juan
    Gonzalez-Millan, Cristina
    Abian-Vicen, Javier
    Soriano, Lidon
    Ruiz, Diana
    Gallo, Cesar
    Lara, Beatriz
    Calleja-Gonzalez, Julio
    [J]. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, 2014, 114 (03) : 587 - 595
  • [7] ACE Activity and Endurance Performance during the South African Ironman Triathlons
    Domingo, R.
    Sturrock, E. D.
    Collins, M.
    [J]. INTERNATIONAL JOURNAL OF SPORTS MEDICINE, 2013, 34 (05) : 402 - 408
  • [8] Neural Mechanisms Underlying 5-HTTLPR-Related Sensitivity to Acute Stress
    Drabant, Emily M.
    Ramel, Wiveka
    Edge, Michael D.
    Hyde, Luke W.
    Kuo, Janice R.
    Goldin, Philippe R.
    Hariri, Ahmad R.
    Gross, James J.
    [J]. AMERICAN JOURNAL OF PSYCHIATRY, 2012, 169 (04) : 397 - 405
  • [9] Genetic Variation of the Human ACE and ACTN3 Genes and Their Association With Functional Muscle Properties in Lithuanian Elite Athletes
    Gineviciene, Valentina
    Pranculis, Aidas
    Jakaitiene, Audrone
    Milasius, Kazys
    Kucinskas, Vaidutis
    [J]. MEDICINA-LITHUANIA, 2011, 47 (05): : 284 - 290
  • [10] Association of 5HTTLPR with factors related to risk of suicide
    Gonda, X.
    Lazary, J.
    Rihmer, Z.
    Bagdy, G.
    [J]. EUROPEAN PSYCHIATRY, 2008, 23 : S175 - S176
12345