First genome-wide association study to identify novel genes related to irinotecan toxicity

被引：0
作者：
Peters, Godefridus J. [1 ]
Giovannetti, Elisa [1 ]
机构：
[1] Vrije Univ Amsterdam, Med Ctr, Dept Med Oncol, NL-1081 HV Amsterdam, Netherlands
来源：
PHARMACOGENOMICS | 2012年 / 13卷 / 13期
关键词：
CELL LUNG-CANCER; PHARMACOKINETICS; POLYMORPHISMS; PROTEIN; ABCC2; 1A1;
D O I：
10.2217/PGS.12.134
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：1445 / 1446
页数：2
相关论文
共 9 条
[1]   Irinotecan-induced diarrhea: Functional significance of the polymorphic ABCC2 transporter protein [J].
de Jong, F. A. ;
Scott-Horton, T. J. ;
Kroetz, D. L. ;
McLeod, H. L. ;
Friberg, L. E. ;
Mathijssen, R. H. ;
Verweij, J. ;
Marsh, S. ;
Sparreboom, A. .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2007, 81 (01) :42-49
[2]  
Giovannetti E, 2012, PHARMACOGENOMICS, V13, P1073, DOI [10.2217/pgs.12.91, 10.2217/PGS.12.91]
[3]   Influence of the organic anion-transporting polypeptide 1B1 (OATP1B1) polymorphisms on irinotecan-pharmacokinetics and clinical outcome of patients with advanced non-small cell lung cancer [J].
Han, Ji-Youn ;
Lim, Hyeong-Seok ;
Shin, Eun Soon ;
Yoo, Yeon-Kyeong ;
Park, Yong Hoon ;
Lee, Jong-Eun ;
Kim, Heung Tae ;
Lee, Jin Soo .
LUNG CANCER, 2008, 59 (01) :69-75
[4]   Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan-pharmacokinetics and clinical outcome in patients with advanced non-small cell lung cancer [J].
Han, Ji-Youn ;
Lim, Hyeong-Seok ;
Yoo, Yeon-Kyeong ;
Shin, Eun Soon ;
Park, Yong Hoon ;
Lee, Sung Young ;
Lee, Jong-Eun ;
Lee, Dea Ho ;
Kim, Heung Tae ;
Lee, Jin Soo .
CANCER, 2007, 110 (01) :138-147
[5]   Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin [J].
Han, Ji-Youn ;
Lim, Hyeong-Seok ;
Shin, Eun Soon ;
Yoo, Yeon-Kyeong ;
Park, Yong Hoon ;
Lee, Jong-Eun ;
Jang, In-Jin ;
Lee, Doe Ho ;
Lee, Jin Soo .
JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (15) :2237-2244
[6]  
Han JY, 2012, PHARMACOGENOMICS J, DOI [10.1038/tpj.24, DOI 10.1038/TPJ.24]
[7]   Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan [J].
Innocenti, F ;
Undevia, SD ;
Iyer, L ;
Chen, PX ;
Das, S ;
Kocherginsky, M ;
Karrison, T ;
Janisch, L ;
Ramírez, J ;
Rudin, CM ;
Vokes, EE ;
Ratain, MJ .
JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (08) :1382-1388
[8]   Uridine diphosphate glucuronosyltransferase (UGT) 1A1 and irinotecan: Practical pharmacogenomics arrives in cancer therapy [J].
O'Dwyer, Peter J. ;
Catalano, Robert B. .
JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (28) :4534-4538
[9]  
Schellens JHM, 2000, ANN NY ACAD SCI, V922, P188
1