Cognition assessment using the NIH Toolbox

被引:948
作者
Weintraub, Sandra [1 ]
Dikmen, Sureyya S. [2 ]
Heaton, Robert K. [3 ]
Tulsky, David S. [4 ]
Zelazo, Philip D. [5 ]
Bauer, Patricia J. [6 ]
Carlozzi, Noelle E. [4 ]
Slotkin, Jerry [7 ]
Blitz, David [7 ]
Wallner-Allen, Kathleen [8 ]
Fox, Nathan A. [9 ]
Beaumont, Jennifer L. [7 ]
Mungas, Dan [10 ]
Nowinski, Cindy J. [7 ]
Richler, Jennifer [11 ]
Deocampo, Joanne A. [6 ]
Anderson, Jacob E. [5 ]
Manly, Jennifer J. [12 ]
Borosh, Beth [1 ]
Havlik, Richard [8 ]
Conway, Kevin [13 ]
Edwards, Emmeline [14 ]
Freund, Lisa [15 ]
King, Jonathan W. [16 ]
Moy, Claudia [17 ]
Witt, Ellen [18 ]
Gershon, Richard C. [7 ]
机构
[1] Northwestern Feinberg Sch Med, Cognit Neurol & Alzheimers Dis Ctr, Chicago, IL USA
[2] Univ Washington, Dept Rehabil Med, Seattle, WA 98195 USA
[3] Univ Calif San Diego, Dept Psychiat, San Diego, CA 92103 USA
[4] Univ Michigan, Dept Phys Med & Rehabil, Ann Arbor, MI 48109 USA
[5] Univ Minnesota, Inst Child Dev, Minneapolis, MN 55455 USA
[6] Emory Univ, Dept Psychol, Atlanta, GA 30322 USA
[7] Northwestern Univ, Dept Med Social Sci, Chicago, IL 60611 USA
[8] Westat Corp, Rockville, MD USA
[9] Univ Maryland, Dept Human Dev, College Pk, MD 20742 USA
[10] Univ Calif Davis, Dept Neurol, Davis, CA 95616 USA
[11] Indiana Univ, Dept Psychol & Brain Sci, Bloomington, IN USA
[12] Columbia Univ, Gertrude H Sergievsky Ctr, Taub Inst Res Alzheimers Dis & Aging Brain, Cognit Neurosci Div, New York, NY 10027 USA
[13] NIDA, Rockville, MD USA
[14] Natl Ctr Complementary & Alternat Med, Bethesda, MD USA
[15] NICHHD, Bethesda, MD 20892 USA
[16] NIA, Bethesda, MD 20892 USA
[17] NINDS, Bethesda, MD 20892 USA
[18] NIAAA, Bethesda, MD USA
关键词
NEUROPSYCHOLOGICAL TEST-PERFORMANCE; CHILDRENS WORKING-MEMORY; EXECUTIVE FUNCTION; PROCESSING SPEED; BRAIN; SPAN; LIFE; INTELLIGENCE; CHILDHOOD; ATTENTION;
D O I
10.1212/WNL.0b013e3182872ded
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Cognition is 1 of 4 domains measured by the NIH Toolbox for the Assessment of Neurological and Behavioral Function (NIH-TB), and complements modules testing motor function, sensation, and emotion. On the basis of expert panels, the cognition subdomains identified as most important for health, success in school and work, and independence in daily functioning were Executive Function, Episodic Memory, Language, Processing Speed, Working Memory, and Attention. Seven measures were designed to tap constructs within these subdomains. The instruments were validated in English, in a sample of 476 participants ranging in age from 3 to 85 years, with representation from both sexes, 3 racial/ethnic categories, and 3 levels of education. This report describes the development of the Cognition Battery and presents results on test-retest reliability, age effects on performance, and convergent and discriminant construct validity. The NIH-TB Cognition Battery is intended to serve as a brief, convenient set of measures to supplement other outcome measures in epidemiologic and longitudinal research and clinical trials. With a computerized format and national standardization, this battery will provide a "common currency" among researchers for comparisons across a wide range of studies and populations. Neurology (R) 2013; 80 (Suppl 3):S54-S64
引用
收藏
页码:S54 / S64
页数:11
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