Systemic Lupus Erythematosus in Children and Adolescents

被引：220

作者：

Levy, Deborah M. ^{[1
]}

Kamphuis, Sylvia ^{[2
,3
,4
]}

机构：

[1] Univ Toronto, Hosp Sick Children, Div Rheumatol, Toronto, ON M5G 1X8, Canada

[2] Erasmus Univ MC, Sophia Childrens Hosp, Div Infectiol, NL-3000 CB Rotterdam, Netherlands

[3] Erasmus Univ MC, Sophia Childrens Hosp, Div Immunol, NL-3000 CB Rotterdam, Netherlands

[4] Erasmus Univ MC, Sophia Childrens Hosp, Div Rheumatol, NL-3000 CB Rotterdam, Netherlands

来源：

PEDIATRIC CLINICS OF NORTH AMERICA | 2012年 / 59卷 / 02期

关键词：

Pediatric; Clinical features; Neuropsychiatric; Nephritis; Diagnosis; Treatment; Complications; QUALITY-OF-LIFE; DISEASE-ACTIVITY; NEUROCOGNITIVE IMPAIRMENT; CLINICAL-FEATURES; REVISED CRITERIA; ONSET; COHORT; PREVALENCE; INFECTIONS; NEPHRITIS;

D O I：

10.1016/j.pcl.2012.03.007

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a wide range of disease manifestations that can involve any organ system, and can lead to significant morbidity and even mortality. This article reviews the epidemiology, common clinical features, and complications of the disease, and briefly discusses the available treatment options. In addition, important medical and psychosocial issues relevant to the pediatrician caring for children and adolescents with SLE are discussed.

引用

页码：345 / +

页数：21

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