Urea-dithiocarbamic acid functionalized magnetic nanoparticles modified with Ch-Cl: Catalytic application for the synthesis of novel hybrid pyridones via cooperative geminal-vinylogous anomeric-based oxidation

This investigation was focused on the novel magnetic nanoparticles anchored deep eutectic solvent namely Fe3O4@SiO2@(CH2)3-urea-dithiocarbamic acid/Ch-Cl as a heterogeneous catalyst. The formation of the catalyst was confirmed by several techniques including FT-IR spectroscopy, FE-SEM, TEM, EDX, ele-mental mapping, TGA/DTG and VSM analysis. Fe3O4@SiO2@(CH2)3-urea-dithiocarbamic acid/Ch-Cl was applied as environmentally sustainable and recoverable catalyst for the synthesis of novel hybrid pyri-dones containing triazole and sulfonamide moieties. X-ray crystallography was also used for the accurate determination of the structure of hybrid pyridones. In addition, based on revealed results, pyridone iso-mer was solely confirmed compared to its relevant tautomer (pyridine). In the current study, cooperative geminal-vinylogous anomeric-based oxidation concept has been used for suggesting a plausible mecha-nism for the synthesis of target molecules. (c) 2022 Elsevier B.V. All rights reserved.