Long-Term Faithful Recapitulation of Transglutaminase 1-Deficient Lamellar Ichthyosis in a Skin-Humanized Mouse Model, and Insights from Proteomic Studies

被引：24
作者：
Aufenvenne, Karin [1 ]
Rice, Robert H. [2 ]
Hausser, Ingrid [3 ]
Oji, Vinzenz [1 ]
Hennies, Hans Christian [4 ]
Del Rio, Marcela [5 ,6 ,7 ]
Traupe, Heiko [1 ]
Larcher, Fernando [5 ,6 ,7 ]
机构：
[1] Univ Hosp Munster, Dept Dermatol, Munster, Germany
[2] Univ Calif Davis, Dept Environm Toxicol, Davis, CA 95616 USA
[3] Univ Heidelberg Hosp, Dept Dermatol, Heidelberg, Germany
[4] Univ Cologne, Cologne Ctr Genom, Div Dermatogenet, D-50931 Cologne, Germany
[5] CIEMAT, Epithelial Biomed Div, E-28040 Madrid, Spain
[6] CIBERER U714, Madrid, Spain
[7] Carlos III Univ UC3M, Dept Bioengn, Madrid, Spain
来源：
JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2012年 / 132卷 / 07期
关键词：
MICE LACKING; GENE; DEATH;
D O I：
10.1038/jid.2012.65
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
引用
收藏
页码：1918 / 1921
页数：4
相关论文
共 12 条
  • [1] The cornified envelope: A model of cell death in the skin
    Candi, E
    Schmidt, R
    Melino, G
    [J]. NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2005, 6 (04) : 328 - 340
  • [2] Direct cutaneous gene delivery in a human genetic skin disease
    Choate, KA
    Khavari, PA
    [J]. HUMAN GENE THERAPY, 1997, 8 (14) : 1659 - 1665
  • [3] Corrective gene transfer in the human skin disorder lamellar ichthyosis
    Choate, KA
    Medalie, DA
    Morgan, JR
    Khavari, PA
    [J]. NATURE MEDICINE, 1996, 2 (11) : 1263 - 1267
  • [4] Novel transglutaminase-1 mutations and genotype-phenotype investigations of 104 patients with autosomal recessive congenital ichthyosis in the USA
    Farasat, S.
    Wei, M-H
    Herman, M.
    Liewehr, D. J.
    Steinberg, S. M.
    Bale, S. J.
    Fleckman, P.
    Toro, J. R.
    [J]. JOURNAL OF MEDICAL GENETICS, 2009, 46 (02) : 103 - 111
  • [5] Development of Skin-Humanized Mouse Models of Pachyonychia Congenita
    Garcia, Marta
    Larcher, Fernando
    Hickerson, Robyn P.
    Baselga, Eulalia
    Leachman, Sancy A.
    Kaspar, Roger L.
    Del Rio, Marcela
    [J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2011, 131 (05) : 1053 - 1060
  • [6] Kuramoto N, 2002, J CLIN INVEST, V109, P243, DOI 10.1172/JCI200213563
  • [7] From cloning and expression of human keratinocyte proline-rich protein (hKPRP), an epidermal marker isolated from calcium-induced differentiating keratinocytes
    Lee, WH
    Jang, SH
    Lee, JS
    Lee, Y
    Seo, EY
    You, KH
    Lee, SC
    Nam, KI
    Kim, JM
    Kee, SH
    Yang, JM
    Seo, YJ
    Park, JK
    Kim, CD
    Lee, JH
    [J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2005, 125 (05) : 995 - 1000
  • [8] Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase)
    Matsuki, M
    Yamashita, F
    Ishida-Yamamoto, A
    Yamada, K
    Kinoshita, C
    Fushiki, S
    Ueda, E
    Morishima, Y
    Tabata, K
    Yasuno, H
    Hashida, M
    Iizuka, H
    Ikawa, M
    Okabe, M
    Kondoh, G
    Kinoshita, T
    Takeda, J
    Yamanishi, K
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (03) : 1044 - 1049
  • [9] Interleukin-1 alpha blockade prevents hyperkeratosis in an in vitro model of lamellar ichthyosis
    O'Shaughnessy, Ryan F. L.
    Choudhary, Ishaan
    Harper, John I.
    [J]. HUMAN MOLECULAR GENETICS, 2010, 19 (13) : 2594 - 2605
  • [10] Oji V, 2006, EUR J DERMATOL, V16, P349
12