Long-Term Faithful Recapitulation of Transglutaminase 1-Deficient Lamellar Ichthyosis in a Skin-Humanized Mouse Model, and Insights from Proteomic Studies

被引：23

作者：

Aufenvenne, Karin ^{[1
]}

Rice, Robert H. ^{[2
]}

Hausser, Ingrid ^{[3
]}

Oji, Vinzenz ^{[1
]}

Hennies, Hans Christian ^{[4
]}

Del Rio, Marcela ^{[5
,6
,7
]}

Traupe, Heiko ^{[1
]}

Larcher, Fernando ^{[5
,6
,7
]}

机构：

[1] Univ Hosp Munster, Dept Dermatol, Munster, Germany

[2] Univ Calif Davis, Dept Environm Toxicol, Davis, CA 95616 USA

[3] Univ Heidelberg Hosp, Dept Dermatol, Heidelberg, Germany

[4] Univ Cologne, Cologne Ctr Genom, Div Dermatogenet, D-50931 Cologne, Germany

[5] CIEMAT, Epithelial Biomed Div, E-28040 Madrid, Spain

[6] CIBERER U714, Madrid, Spain

[7] Carlos III Univ UC3M, Dept Bioengn, Madrid, Spain

来源：

JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2012年 / 132卷 / 07期

关键词：

MICE LACKING; GENE; DEATH;

D O I：

10.1038/jid.2012.65

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

引用

页码：1918 / 1921

页数：4

共 12 条

[1] The cornified envelope: A model of cell death in the skin [J].

Candi, E ;

Schmidt, R ;

Melino, G .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2005, 6 (04) :328-340

[2] Direct cutaneous gene delivery in a human genetic skin disease [J].

Choate, KA ;

Khavari, PA .

HUMAN GENE THERAPY, 1997, 8 (14) :1659-1665

[3] Corrective gene transfer in the human skin disorder lamellar ichthyosis [J].

Choate, KA ;

Medalie, DA ;

Morgan, JR ;

Khavari, PA .

NATURE MEDICINE, 1996, 2 (11) :1263-1267

[4] Novel transglutaminase-1 mutations and genotype-phenotype investigations of 104 patients with autosomal recessive congenital ichthyosis in the USA [J].

Farasat, S. ;

Wei, M-H ;

Herman, M. ;

Liewehr, D. J. ;

Steinberg, S. M. ;

Bale, S. J. ;

Fleckman, P. ;

Toro, J. R. .

JOURNAL OF MEDICAL GENETICS, 2009, 46 (02) :103-111

[5] Development of Skin-Humanized Mouse Models of Pachyonychia Congenita [J].

Garcia, Marta ;

Larcher, Fernando ;

Hickerson, Robyn P. ;

Baselga, Eulalia ;

Leachman, Sancy A. ;

Kaspar, Roger L. ;

Del Rio, Marcela .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2011, 131 (05) :1053-1060

[6]

Kuramoto N, 2002, J CLIN INVEST, V109, P243, DOI 10.1172/JCI200213563

[7] From cloning and expression of human keratinocyte proline-rich protein (hKPRP), an epidermal marker isolated from calcium-induced differentiating keratinocytes [J].

Lee, WH ;

Jang, SH ;

Lee, JS ;

Lee, Y ;

Seo, EY ;

You, KH ;

Lee, SC ;

Nam, KI ;

Kim, JM ;

Kee, SH ;

Yang, JM ;

Seo, YJ ;

Park, JK ;

Kim, CD ;

Lee, JH .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2005, 125 (05) :995-1000

[8] Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase) [J].

Matsuki, M ;

Yamashita, F ;

Ishida-Yamamoto, A ;

Yamada, K ;

Kinoshita, C ;

Fushiki, S ;

Ueda, E ;

Morishima, Y ;

Tabata, K ;

Yasuno, H ;

Hashida, M ;

Iizuka, H ;

Ikawa, M ;

Okabe, M ;

Kondoh, G ;

Kinoshita, T ;

Takeda, J ;

Yamanishi, K .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (03) :1044-1049

[9] Interleukin-1 alpha blockade prevents hyperkeratosis in an in vitro model of lamellar ichthyosis [J].

O'Shaughnessy, Ryan F. L. ;

Choudhary, Ishaan ;

Harper, John I. .

HUMAN MOLECULAR GENETICS, 2010, 19 (13) :2594-2605

[10]

Oji V, 2006, EUR J DERMATOL, V16, P349

← 1 2 →