During the structural analysis of cable-stayed bridges, some specific problems arise that are not common in other types of bridges. One of these problem is the derivation of an optimal sequence for the tensioning of the stay cables. This paper describes a novel solution to this problem, the unit force method. The method takes into account all relevant effects for the design of cable-stayed bridges, including construction sequence, second-order theory, large displacements, cable sag and time-dependent effects, such as creep and shrinkage or relaxation of prestressing tendons. Information about the implementation of this method into a computer program is given, and an example of a practical application of this method concludes this paper. The method is not restricted to the design of cable-stayed bridges and may well be used for other structural applications in the future.