The KQ element, a complex genetic region conferring transferable resistance to carbapenems, aminoglycosides, and fluoroquinolones in Klebsiella pneumoniae

被引：57

作者：

Rice, Louis B. ^{[1
,2
]}

Carias, Lenore L. ^{[1
]}

Hutton, Rebecca A. ^{[2
]}

Rudin, Susan D. ^{[1
]}

Endimiani, Andrea ^{[1
]}

Bonomo, Robert A. ^{[1
,2
]}

机构：

[1] Louis Stokes Cleveland VA Med Ctr, Med & Res Serv, Cleveland, OH 44106 USA

[2] Case Western Reserve Univ, Sch Med, Dept Med, Cleveland, OH 44106 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2008年 / 52卷 / 09期

关键词：

D O I：

10.1128/AAC.00493-08

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The bla(KPC-3) and qnrB19 determinants of transferable Klebsiella pneumoniae plasmid pLRM24 reside within a complex region consisting of a Tn1331 backbone into which a Tn4401-like element and qnrB19 mobilized by an adjacent ISEcp1 insertion sequence have been inserted. This novel element represents a coalescence of genes conferring multidrug resistance in K. pneumoniae.

引用

页码：3427 / 3429

页数：3

共 19 条

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