An 8-month randomized controlled exercise trial alters brain activation during cognitive tasks in overweight children

被引：161

作者：

Krafft, Cynthia E. ^{[1
]}

Schwarz, Nicolette F. ^{[1
]}

Chi, Lingxi ^{[1
]}

Weinberger, Abby L. ^{[1
]}

Schaeffer, David J. ^{[2
]}

Pierce, Jordan E. ^{[1
]}

Rodrigue, Amanda L. ^{[1
]}

Yanasak, Nathan E. ^{[3
]}

Miller, Patricia H. ^{[4
]}

Tomporowski, Phillip D. ^{[5
]}

Davis, Catherine L. ^{[6
,7
]}

McDowell, Jennifer E. ^{[1
,2
]}

机构：

[1] Univ Georgia, Dept Psychol, Athens, GA 30602 USA

[2] Univ Georgia, Dept Neurosci, Athens, GA 30602 USA

[3] Georgia Regents Univ, Med Coll Georgia, Dept Radiol, Augusta, GA USA

[4] San Francisco State Univ, Dept Psychol, San Francisco, CA 94132 USA

[5] Univ Georgia, Dept Kinesiol, Athens, GA 30602 USA

[6] Georgia Regents Univ, Med Coll Georgia, Georgia Prevent Ctr, Augusta, GA USA

[7] Georgia Regents Univ, Med Coll Georgia, Dept Pediat, Augusta, GA USA

来源：

OBESITY | 2014年 / 22卷 / 01期

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

EVENT-RELATED FMRI; RESPONSE COMPETITION; ACADEMIC-ACHIEVEMENT; PHYSICAL-ACTIVITY; AEROBIC FITNESS; CONFLICT; MRI; PERFORMANCE; INHIBITION; TRANSIENT;

D O I：

10.1002/oby.20518

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objective Children who are less fit reportedly have lower performance on tests of cognitive control and differences in brain function. This study examined the effect of an exercise intervention on brain function during two cognitive control tasks in overweight children. Design and Methods Participants included 43 unfit, overweight (BMI 85th percentile) children 8- to 11-years old (91% Black), who were randomly divided into either an aerobic exercise (n=24) or attention control group (n=19). Each group was offered a separate instructor-led after-school program every school day for 8 months. Before and after the program, all children performed two cognitive control tasks during functional magnetic resonance imaging (fMRI): antisaccade and flanker. Results Compared to the control group, the exercise group decreased activation in several regions supporting antisaccade performance, including precentral gyrus and posterior parietal cortex, and increased activation in several regions supporting flanker performance, including anterior cingulate and superior frontal gyrus. Conclusions Exercise may differentially impact these two task conditions, or the paradigms in which cognitive control tasks were presented may be sensitive to distinct types of brain activation that show different effects of exercise. In sum, exercise appears to alter efficiency or flexible modulation of neural circuitry supporting cognitive control in overweight children.

引用

页码：232 / 242

页数：11

共 40 条

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