Women with HNPCC: A target population for the chemoprevention of gynecologic cancers

被引：0
作者：
Broaddus, RR
Lu, KH
机构：
[1] Univ Texas, MD Anderson Canc Ctr, Dept Pathol, Houston, TX 77030 USA
[2] Univ Texas, MD Anderson Canc Ctr, Dept Gynecol Oncol, Houston, TX 77030 USA
来源：
FRONTIERS IN BIOSCIENCE | 2006年 / 11卷
关键词：
endometrium; ovary; cancer; tumor; neoplasia; adenocarcinoma; endometrioid carcinoma; HNPCC; gynecologic cancer; endometrial cancer; review;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Hereditary nonpolyposis colorectal cancer syndrome (HNPCC) is an autosomal-dominant inherited cancer susceptibility syndrome that is associated with increased risk of development of endometrial and ovarian cancers. Therefore, women with HNPCC are candidates for chemoprevention of gynecological cancers. Although there have been a number of clinical trials examining chemoprevention strategies for colorectal cancer in HNPCC, the information regarding gynecological cancers in HNPCC remains limited. The purpose of this review is to provide an analytical background about the current knowledge regarding gynecological cancers in patients with HNPCC.
引用
收藏
页码：2077 / 2080
页数：4
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