Alcohol Amination with Aminoacidato Cp*Ir(III)-Complexes as Catalysts: Dissociation of the Chelating Ligand during Initiation

被引：28
作者：
Woeckel, Simone [1 ]
Plessow, Philipp [1 ,2 ]
Schelwies, Mathias [3 ]
Brinks, Marion K. [3 ]
Rominger, Frank [4 ]
Hofmann, Peter [1 ,4 ]
Limbach, Michael [1 ,3 ]
机构：
[1] CaRLa Catalysis Res Lab, D-69120 Heidelberg, Germany
[2] BASF SE, Quantum Chem, D-67056 Ludwigshafen, Germany
[3] BASF SE, Synth & Homogenous Catalysis, D-67056 Ludwigshafen, Germany
[4] Heidelberg Univ, Inst Organ Chem, D-69120 Heidelberg, Germany
来源：
ACS CATALYSIS | 2014年 / 4卷 / 01期
关键词：
alcohol amination; hydrogen borrowing; iridium; sandwich complexes; amino acids; BIOLOGICALLY IMPORTANT LIGANDS; N-HETEROCYCLIC CARBENE; ASTERISK-IR COMPLEX; GAUSSIAN-BASIS SETS; METAL-COMPLEXES; HALFSANDWICH COMPLEXES; TRANSFER HYDROGENATION; EFFICIENT CATALYSTS; ACID COMPLEXES; PRIMARY AMINES;
D O I：
10.1021/cs4009418
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The use of aminoacidato Cp*Ir(III)-complexes in catalytic alcohol amination reactions of primary and secondary alcohols with amines permits to carry out these transformations at very mild reaction conditions without the use of an additional base. Herein we discuss the fate of the chelating aminoacidato ligands upon initiation of Cp*Ir(III)complexes from a mechanistic perspective. Catalyst initiation has been followed by NMR using isotopically labeled C-13,N-15-glycinato complexes.
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收藏
页码：152 / 161
页数：10
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