Chronic Hepatitis E in HIV Patients: Rapid Progression to Cirrhosis and Response to Oral Ribavirin

被引:90
作者
Neukam, Karin [1 ,2 ]
Barreiro, Pablo [3 ]
Macias, Juan [1 ,2 ]
Avellon, Ana [4 ]
Cifuentes, Celia [1 ,2 ]
Martin-Carbonero, Luz [3 ]
Echevarria, Jose M. [4 ]
Vargas, Julio [1 ,2 ]
Soriano, Vicente [3 ]
Pineda, Juan A. [1 ,2 ]
机构
[1] Hosp Univ Valme, Unit Infect Dis & Microbiol, Seville, Spain
[2] Inst Biomed Sevilla, Madrid, Spain
[3] Hosp Carlos III, Dept Infect Dis, Madrid, Spain
[4] Inst Salud Carlos III, Natl Ctr Microbiol, Majadahonda, Spain
关键词
chronic hepatitis E; HIV; cirrhosis; ribavirin; immunosuppression; E VIRUS-INFECTION; SPAIN; HEV;
D O I
10.1093/cid/cit224
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Chronic hepatitis E virus infection with rapid progression to cirrhosis is reported in 2 human immunodeficiency virus (HIV)-infected patients with severe immunosuppression. Monotherapy with ribavirin led to temporary viral response and marked improvement of liver damage. Chronic hepatitis E should be regarded as another opportunistic event within HIV infection.
引用
收藏
页码:465 / 468
页数:4
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