Contemporary Synthetic Strategies towards Secosteroids, abeo -Steroids, and Related Triterpenes

被引:32
|
作者
Noack, Florian [1 ]
Heinze, Robert C. [1 ]
Heretsch, Philipp [1 ]
机构
[1] Free Univ Berlin, Inst Chem & Biochem, Takustr 3, D-14195 Berlin, Germany
来源
SYNTHESIS-STUTTGART | 2019年 / 51卷 / 10期
关键词
abeo; -steroids; biomimetic synthesis; secosteroids; semisynthesis; total synthesis; triterpenes; MONO-D-THEVETOSIDE; DRUG PAI-CHIEN; GLAUCOGENIN-A; EFFICIENT; RADICALS; ALCOHOLS; FRAGMENTATION; CONSTRUCTION; OXIDATION; ALDEHYDES;
D O I
10.1055/s-0037-1611576
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Steroids have long been sought after as synthetic targets. Their rearranged counterparts, though, have only recently received more attention, when isolation and biological testing programs revealed several molecular entities that were both structurally intriguing as well as biologically relevant. This review will highlight contemporary synthetic approaches towards the growing class of seco- and abeo -steroids and some related triterpenoid natural products.
引用
收藏
页码:2039 / 2057
页数:19
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