Advances in Supercritical Fluid Chromatography for the Analysis of Chiral and Achiral Pharmaceuticals

被引：0
作者：
De Klerck, Katrijn [1 ]
Mangelings, Debby [1 ]
Vander Heyden, Yvan [1 ]
机构：
[1] Vrije Univ Brussel, Pharmaceut Res Ctr, Dept Analyt Chem & Pharmaceut Technol, Brussels, Belgium
来源：
LC GC EUROPE | 2013年
关键词：
LIQUID-CHROMATOGRAPHY; STATIONARY PHASES; COLUMN; SEPARATIONS; PARTICLES; SILICA; ENANTIOSEPARATIONS; PERFORMANCE; ENVIRONMENT; MOLECULES;
D O I：
暂无
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A revival of supercritical fluid chromatography (SFC) has been observed recently. SFC has repeatedly enabled fast and efficient separations, and in some cases has even outperformed high performance liquid chromatography (HPLC). This article provides an overview of the most recent advances in the field of chiral and achiral separations in SFC. This involves research focused on the most critical parameters in SFC separations, but also on practical issues such as the serial coupling of columns. The recent evolution from classic SFC to ultrahigh-performance supercritical fluid chromatography (UPSFC) is also discussed.
引用
收藏
页码：24 / +
页数：6
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