Dynapenic Abdominal Obesity Increases Mortality Risk Among English and Brazilian Older Adults: A 10-Year Follow-Up of the ELSA and SABE Studies

被引:40
作者
Alexandre, T. da Silva [1 ,2 ]
Scholes, S. [1 ]
Ferreira Santos, J. L. [3 ]
De Oliveira Duarte, Y. A. [4 ]
De Oliveira, C. [1 ]
机构
[1] UCL, Dept Epidemiol & Publ Hlth, London, England
[2] Univ Fed Sao Carlos, Dept Gerontol, Sao Carlos, SP, Brazil
[3] Univ Sao Paulo, Dept Social Med, Ribeirao Preto, Brazil
[4] Univ Sao Paulo, Dept Med Surg Nursing, Sao Paulo, Brazil
基金
巴西圣保罗研究基金会;
关键词
Dynapenia; handgrip; waist circumference; obesity; mortality; MUSCLE MASS; CIGARETTE-SMOKING; COHORT PROFILE; BODY-FAT; HEALTH; STRENGTH; ASSOCIATIONS; DISABILITY; SARCOPENIA; WEIGHT;
D O I
10.1007/s12603-017-0966-4
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
There is little epidemiological evidence demonstrating that dynapenic abdominal obesity has higher mortality risk than dynapenia and abdominal obesity alone. Our main aim was to investigate whether dynapenia combined with abdominal obesity increases mortality risk among English and Brazilian older adults over ten-year follow-up. Cohort study. United Kingdom and Brazil. Data came from 4,683 individuals from the English Longitudinal Study of Ageing (ELSA) and 1,490 from the Brazilian Health, Well-being and Aging study (SABE), hence the final sample of this study was 6,173 older adults. The study population was categorized into the following groups: nondynapenic/ non-abdominal obese, abdominal obese, dynapenic, and dynapenic abdominal obese according to their handgrip strength (< 26 kg for men and < 16 kg for women) and waist circumference (> 102 cm for men and > 88 cm for women). The outcome was all-cause mortality over a ten-year follow-up. Adjusted hazard ratios by sociodemographic, behavioural and clinical characteristics were estimated using Cox proportional hazards models. Results: The fully adjusted model showed that dynapenic abdominal obesity has a higher mortality risk among the groups. The hazard ratios (HR) were 1.37 for dynapenic abdominal obesity (95% CI = 1.12-1.68), 1.15 for abdominal obesity (95% CI = 0.98-1.35), and 1.23 for dynapenia (95% CI = 1.04-1.45). Dynapenia is an important risk factor for mortality but dynapenic abdominal obesity has the highest mortality risk among English and Brazilian older adults.
引用
收藏
页码:138 / 144
页数:7
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