Experimental infection models and susceptibility of Atlantic salmon Salmo salar to a Scottish isolate of infectious salmon anaemia virus

被引:33
作者
Raynard, RS [1 ]
Snow, M [1 ]
Bruno, DW [1 ]
机构
[1] FRS Marine Lab, Aberdeen AB11 9DB, Scotland
关键词
infectious salmon anaemia virus; Atlantic salmon; Salmo salar; experimental infection;
D O I
10.3354/dao047169
中图分类号
S9 [水产、渔业];
学科分类号
0908 ;
摘要
Infection models for both fresh and seawater salmon were established using a Scottish isolate of infectious salmon anaemia virus (ISAV). Modes of infection were intra-peritoneal injection, cohabitation and immersion exposure, and a range of doses was tested. Development of these models using a Scottish isolate of ISAV provided an approximation of the minimum infective dose leading to mortality under different infection regimens. The models also allow prediction of the time to first mortality and an estimation of expected total mortality following the various routes of infection. Such knowledge is important to the development of anti-ISAV vaccines and to future studies aimed at understanding the biology of ISAV in general.
引用
收藏
页码:169 / 174
页数:6
相关论文
共 29 条
[21]  
Rodger H.D., 1998, Bulletin of the European Association of Fish Pathologists, V18, P115
[22]   Experimental susceptibility of turbot Scophthalmus maximus to viral haemorrhagic septicaemia virus isolated from cultivated turbot [J].
Snow, M ;
Smail, DA .
DISEASES OF AQUATIC ORGANISMS, 1999, 38 (03) :163-168
[23]  
Stagg R., 1999, State Veterinary Journal, V9, P1
[24]  
Thompson S.K., 1992, WILEY SERIES PROBABI
[25]  
Thorud K., 1988, Bulletin of the European Association of Fish Pathologists, V8, P109
[26]   Transmission of infectious salmon anaemia (ISA) through natural secretions and excretions from infected smelts of Atlantic salmon Salmo salar during their presymptomatic phase [J].
Totland, GK ;
Hjeltnes, BK ;
Flood, PR .
DISEASES OF AQUATIC ORGANISMS, 1996, 26 (01) :25-31
[27]  
TURNBULL T, 1999, FISH VET J, V3, P64
[28]  
Vagsholm I., 1993, Norsk Veterinartidsskrift, V105, P5
[29]  
2000, FISH FARM INT, V27, P47