Valproate-induced Hyperammonemic Encephalopathy Presenting as Catatonia

被引：4

作者：

Perez-Esparza, Rodrigo ^{[1
,2
]}

Onate-Cadena, Nelcy ^{[1
]}

Ramirez-Bermudez, Jesus ^{[1
]}

Espinola-Nadurille, Mariana ^{[1
]}

机构：

[1] Natl Inst Neurol & Neurosurg, Dept Neuropsychiat, Mexico City, DF, Mexico

[2] Natl Inst Neurol & Neurosurg, Addict Res Lab, Insurgentes Sur 3877, Mexico City 14269, DF, Mexico

来源：

NEUROLOGIST | 2018年 / 23卷 / 02期

关键词：

hyperammonemia; catatonia; valproate; valproic acid; encephalopathy; ACID;

D O I：

10.1097/NRL.0000000000000166

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Hyperammonemic encephalopathy secondary to the use of valproate is rare without evidence of hepatotoxicity, and it usually presents with confusion, agitation, irritability, cognitive disturbances, lethargy, coma, and death. We present the case of a 21-year-old woman presenting with catatonia as a manifestation of hyperammonemic encephalopathy that resolved with the normalization of ammonia and suspension of valproate.

引用

页码：51 / 52

页数：2

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