Synthesis and characterization of new N-substituted 2-aminopyrrole derivatives

被引：5

作者：

Aksu, Kadir ^{[1
]}

Ozgeris, Bunyamin ^{[2
]}

Tumer, Ferhan ^{[3
]}

机构：

[1] Ordu Univ, Chem Dept, Ordu, Turkey

[2] Erzurum Tech Univ, Basic Sci Dept, Erzurum, Turkey

[3] Kahramanmaras Sutcu Imam Univ, Chem Dept, TR-46100 Kahramanmaras, Turkey

来源：

ORGANIC COMMUNICATIONS | 2019年 / 12卷 / 01期

关键词：

Pyrrole; aminopyrrole; Knoevenagel condensation; Gewald reaction; PYRROLE;

D O I：

10.25135/acg.oc.55.19.03.1222

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In this work, new N-substituted 2-aminopyrrole derivatives were synthesized. Initially, some crotonitriles were prepared by condensation of malononitrile with arylmethylketones, which was followed by conversion of them to the bromocrotonitriles. Finally, the synthesis of new N-substituted 2-aminopyrrole derivates were successfully achieved by cyclization of the bromocrotonitriles of (R)-1-phenylethylamine applying Gewald method.

引用

页码：38 / 42

页数：5

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