Synthesis and characterization of new N-substituted 2-aminopyrrole derivatives

被引：5

作者：

Aksu, Kadir ^{[1
]}

Ozgeris, Bunyamin ^{[2
]}

Tumer, Ferhan ^{[3
]}

机构：

[1] Ordu Univ, Chem Dept, Ordu, Turkey

[2] Erzurum Tech Univ, Basic Sci Dept, Erzurum, Turkey

[3] Kahramanmaras Sutcu Imam Univ, Chem Dept, TR-46100 Kahramanmaras, Turkey

来源：

ORGANIC COMMUNICATIONS | 2019年 / 12卷 / 01期

关键词：

Pyrrole; aminopyrrole; Knoevenagel condensation; Gewald reaction; PYRROLE;

D O I：

10.25135/acg.oc.55.19.03.1222

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In this work, new N-substituted 2-aminopyrrole derivatives were synthesized. Initially, some crotonitriles were prepared by condensation of malononitrile with arylmethylketones, which was followed by conversion of them to the bromocrotonitriles. Finally, the synthesis of new N-substituted 2-aminopyrrole derivates were successfully achieved by cyclization of the bromocrotonitriles of (R)-1-phenylethylamine applying Gewald method.

引用

页码：38 / 42

页数：5

共 50 条

[1] Synthesis and Characterization of Some N-substituted Polypyrrole Derivatives: Towards Glucose Sensing Electrodes
Gursoy, Songul Sen
Uygun , Aysegul
Tilki, Tahir
JOURNAL OF MACROMOLECULAR SCIENCE PART A-PURE AND APPLIED CHEMISTRY, 2010, 47 (07): : 681 - 688
[2] Solvent Free Synthesis of N-Substituted Pyrrole Derivatives Catalyzed by Silica Sulfuric Acid
A. J. Khammas
C. Yolacan
F. Aydogan
Russian Journal of General Chemistry, 2018, 88 : 2680 - 2683
[3] Solvent Free Synthesis of N-Substituted Pyrrole Derivatives Catalyzed by Silica Sulfuric Acid
Khammas, A. J.
Yolacan, C.
Aydogan, F.
RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2018, 88 (12) : 2680 - 2683
[4] An efficient synthesis of N-substituted pyrroles catalyzed by MgI2 etherate
Zhang, Yongdong
Weng, Guodong
Chen, Jingyan
Ma, Danting
Zhang, Xingxian
MAIN GROUP METAL CHEMISTRY, 2014, 37 (5-6) : 131 - 135
[5] A facile synthesis of N-substituted 2,5-dimethylpyrroles with saccharin as a green catalyst
Namratha Bhandari
Santosh L. Gaonkar
Chemistry of Heterocyclic Compounds, 2015, 51 : 320 - 323
[6] A facile synthesis of N-substituted 2,5-dimethylpyrroles with saccharin as a green catalyst
Bhandari, Namratha
Gaonkar, Santosh L.
CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2015, 51 (04) : 320 - 323
[7] Rice Malt: A Solvent-Catalyst for the Synthesis of N-Substituted Pyrroles
Yadav, Ram Naresh
Rohand, Taoufik
Banik, Bimal Krishna
CURRENT ORGANOCATALYSIS, 2023, 10 (04) : 276 - 282
[8] N-substituted 2,5-Di(2-thienyl)pyrroles. Synthesis and electrochemical properties
T. S. El’shina
E. A. Sosnin
E. V. Shklyaeva
G. G. Abashev
Russian Journal of General Chemistry, 2013, 83 : 726 - 730
[9] Selective synthesis of N-substituted pyrrolo[1,2-a]pyrazin-1(2H)-one derivatives via alkyne cyclization
Cetinkaya, Yasin
Balci, Metin
TETRAHEDRON LETTERS, 2014, 55 (49) : 6698 - 6702
[10] Iron-Catalyzed Inexpensive and Practical Synthesis of N-Substituted Pyrroles in Water
Azizi, Najmedin
Khajeh-Amiri, Alireza
Ghafuri, Hossein
Bolourtchian, Mohammad
Saidi, Mohammad Reza
SYNLETT, 2009, (14) : 2245 - 2248

← 1 2 3 4 5 →