Quantification of selected monohydroxy metabolites of polycyclic aromatic hydrocarbons in human urine

被引：9

作者：

Liu, Libin ^{[1
]}

Luo, Yueping ^{[1
]}

Bi, Junping ^{[1
]}

Li, Haifang ^{[2
]}

Lin, Jin-Ming ^{[2
]}

机构：

[1] Hunan Prov Environm Monitoring Ctr, Key Lab Monitoring Heavy Met Pollutants, Changsha 410019, Hunan, Peoples R China

[2] Tsinghua Univ, Dept Chem, Beijing Key Lab Microanalyt Methods & Instrumenta, Beijing 100084, Peoples R China

来源：

SCIENCE CHINA-CHEMISTRY | 2015年 / 58卷 / 10期

基金：

中国国家自然科学基金;

关键词：

polycyclic aromatic hydrocarbons; metabolites; human urine; solid-phase microextraction; GC/MS; CHROMATOGRAPHY-MASS-SPECTROMETRY; SOLID-PHASE MICROEXTRACTION; PERFORMANCE LIQUID-CHROMATOGRAPHY; HYDROXYLATED METABOLITES; 1-HYDROXYPYRENE; EXTRACTION; DERIVATIZATION; FLUORESCENCE; PYRENE; POLYETHERETHERKETONE;

D O I：

10.1007/s11426-015-5357-2

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An analytical method was developed to quantitatively determine selected monohydroxy metabolites of polycyclic aromatic hydrocarbons (PAHs) in human urine. The procedure included enzymatic hydrolysis to cleave the conjugated metabolites, solid-phase microextraction enrichment, and gas chromatography-mass spectrometry analysis. The method proved to be sensitive enough to detect the selected PAH metabolites in human urine.

引用

收藏

页码：1579 / 1584

页数：6

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