Diffusive transport through a model host-biofilm system

被引：14

作者：

Aristotelous, A. C. ^{[1
]}

Klapper, I. ^{[1
,2
]}

Grabovsky, Y. ^{[1
]}

Pabst, B. ^{[2
]}

Pitts, B. ^{[2
]}

Stewart, P. S. ^{[2
]}

机构：

[1] Temple Univ, Dept Math, Philadelphia, PA 19122 USA

[2] Montana State Univ, Ctr Biofilm Engn, Bozeman, MT 59717 USA

来源：

PHYSICAL REVIEW E | 2015年 / 92卷 / 02期

基金：

美国国家科学基金会;

关键词：

CYSTIC-FIBROSIS PATIENTS; DISCONTINUOUS GALERKIN; PSEUDOMONAS-AERUGINOSA; MICROBIAL BIOFILMS; INFECTION; EQUATION;

D O I：

10.1103/PhysRevE.92.022703

中图分类号：

O35 [流体力学]; O53 [等离子体物理学];

学科分类号：

070204 ; 080103 ; 080704 ;

摘要：

Free-living biofilms have been subject to considerable attention, and basic physical principles for them are generally accepted. Many host-biofilm systems, however, consist of heterogeneous mixtures of aggregates of microbes intermixed with host material and are much less studied. Here we analyze a key property, namely reactive depletion, in such systems and argue that two regimes are possible: (1) a homogenizable mixture of biofilm and host that in important ways acts effectively like a homogeneous macrobiofilm and (2) a distribution of separated microbiofilms within the host with independent local microenvironments.

引用

页数：7

共 32 条

[1]

[Anonymous], 1978, ASYMPTOTIC ANAL PERI

[2] Adaptive, second-order in time, primitive-variable discontinuous Galerkin schemes for a Cahn-Hilliard equation with a mass source [J].

Aristotelous, Andreas C. ;

Karakashian, Ohannes A. ;

Wise, Steven M. .

IMA JOURNAL OF NUMERICAL ANALYSIS, 2015, 35 (03) :1167-1198

[3] Use of hybrid discrete cellular models for identification of macroscopic nutrient loss in reaction-diffusion models of tissues [J].

Aristotelous, Andreas C. ;

Haider, Mansoor A. .

INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING, 2014, 30 (08) :767-780

[4] A MIXED DISCONTINUOUS GALERKIN, CONVEX SPLITTING SCHEME FOR A MODIFIED CAHN-HILLIARD EQUATION AND AN EFFICIENT NONLINEAR MULTIGRID SOLVER [J].

Aristotelous, Andreas C. ;

Krakashian, Ohannes ;

Wise, Steven M. .

DISCRETE AND CONTINUOUS DYNAMICAL SYSTEMS-SERIES B, 2013, 18 (09) :2211-2238

[5] Unified analysis of discontinuous Galerkin methods for elliptic problems [J].

Arnold, DN ;

Brezzi, F ;

Cockburn, B ;

Marini, LD .

SIAM JOURNAL ON NUMERICAL ANALYSIS, 2002, 39 (05) :1749-1779

[6]

Bird R B., 2002, Transportphenomena

[7] The in vivo biofilm [J].

Bjarnsholt, Thomas ;

Alhede, Maria ;

Alhede, Morten ;

Eickhardt-Sorensen, Steffen R. ;

Moser, Claus ;

Kuhl, Michael ;

Jensen, Peter Ostrup ;

Hoiby, Niels .

TRENDS IN MICROBIOLOGY, 2013, 21 (09) :466-474

[8] Pseudomonas aeruginosa Biofilms in the Respiratory Tract of Cystic Fibrosis Patients [J].

Bjarnsholt, Thomas ;

Jensen, Peter Ostrup ;

Fiandaca, Mark J. ;

Pedersen, Jette ;

Hansen, Christine Ronne ;

Andersen, Claus Bogelund ;

Pressler, Tacjana ;

Givskov, Michael ;

Hoiby, Niels .

PEDIATRIC PULMONOLOGY, 2009, 44 (06) :547-558

[9]

BONA J., 1990, P WORKSHOP VISCOUS N, P117

[10] CONSERVATIVE, HIGH-ORDER NUMERICAL SCHEMES FOR THE GENERALIZED KORTEWEG-DE VRIES EQUATION [J].

BONA, JL ;

DOUGALIS, VA ;

KARAKASHIAN, OA ;

MCKINNEY, WR .

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, 1995, 351 (1695) :107-164

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