Westerdykella reniformis sp nov., producing the antibiotic metabolites melinacidin IV and chetracin B

被引：28

作者：

Ebead, Ghada A. ^{[1
]}

Overy, David P. ^{[2
,3
]}

Berrue, Fabrice ^{[2
,3
]}

Kerr, Russell G. ^{[1
,2
,3
]}

机构：

[1] Univ Prince Edward Isl, Atlantic Vet Coll, Dept Biomed Sci, 550 Univ Ave, Charlottetown, PE C1A 4P3, Canada

[2] Univ Prince Edward Isl, Dept Chem, Charlottetown, PE C1A 4P3, Canada

[3] Duffy Res Ctr NRC INH, Nautilus Biosci Canada, Charlottetown, PE C1A 4P3, Canada

来源：

IMA FUNGUS | 2012年 / 3卷 / 02期

基金：

加拿大自然科学与工程研究理事会;

关键词：

antimicrobial screening; Ascomycota; ITS phylogeny; multigene phylogeny; Sporormiaceae; PHYLOGENETIC-RELATIONSHIPS; DYKELLIC ACID; ASCOMYCOTA; PLEOSPORALES; INHIBITORS; MANGROVE; ROOTS; LAKE;

D O I：

10.5598/imafungus.2012.03.02.11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Westerdykella reniformis Ebead & Overy sp. nov. is described based on morphology and phylogenetic analyses using ITS, nLSU rDNA, and beta-tubulin gene sequences. Westerdykella reniformis is characterized by the production of cleistothecioid ascomata, containing small globose to subglobose asci with 32, aseptate, dark colored, pronouncedly reniform ascospores having a concave central groove. The isolate was obtained from a red alga (Polysiphonia sp.) collected from the tidal zone in Canada at low tide. Organic extracts enriched in extrolites, obtained from fermentation on a rice-based media, inhibited the growth of methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecium (VRE), S. warneri, and Proteus vulgaris. Presented here is the identification of the compounds responsible for the observed antimicrobial activity, the taxonomic description of W. reniformis, and a dichotomous key to the known species of Westerdykella based on macro-and micromorphological characters.

引用

页码：189 / 201

页数：13

共 38 条

[1] The endophytic fungal communities associated with the leaves and roots of the common reed (Phragmites australis) in Lake Trasimeno (Perugia, Italy) in declining and healthy stands [J].