A molecular technique to explore the relationship between Porphyromonas gingivalis and severity of chronic periodontitis: A clinical approach

被引：3
作者：
Gita, J. Bagavad [2 ]
Aishwarya, A. B. [1 ]
Pavithra, N. [1 ]
Chandrasekaran, S. C. [2 ]
George, Ann V. [2 ]
Gnanamani, A. [1 ]
机构：
[1] CSIR CLRI, Microbiol Div, Madras 600020, Tamil Nadu, India
[2] Sree Balaji Dent Coll & Hosp, Madras 600100, Tamil Nadu, India
来源：
ANAEROBE | 2018年 / 49卷
关键词：
Porphyromonas gingivalis; Chronic periodontitis; Clinical severity; Polymerase chain reaction; Image density; DISEASE;
D O I：
10.1016/j.anaerobe.2017.10.011
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Relationship between clinical severities of periodontal disease and the expression of the associated pathogens serve as good indicators of real time disease activity and progression. A double blind study using Image J software carried out to assess the density of the amplified band for Porphyromonas gingivalis in periodontally healthy and disease subjects. Results on image densities of P. gingivalis showed a statistical significance (p < 0.005) between healthy and diseased subjects and also within the various groups of periodontal disease severity. Thus, assessment of relative gel image density can be a simple yet valuable tool to monitor real time periodontal disease activity. (C) 2017 Elsevier Ltd. All rights reserved.
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页码：1 / 4
页数：4
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