A molecular technique to explore the relationship between Porphyromonas gingivalis and severity of chronic periodontitis: A clinical approach

被引：3

作者：

Gita, J. Bagavad ^{[2
]}

Aishwarya, A. B. ^{[1
]}

Pavithra, N. ^{[1
]}

Chandrasekaran, S. C. ^{[2
]}

George, Ann V. ^{[2
]}

Gnanamani, A. ^{[1
]}

机构：

[1] CSIR CLRI, Microbiol Div, Madras 600020, Tamil Nadu, India

[2] Sree Balaji Dent Coll & Hosp, Madras 600100, Tamil Nadu, India

来源：

ANAEROBE | 2018年 / 49卷

关键词：

Porphyromonas gingivalis; Chronic periodontitis; Clinical severity; Polymerase chain reaction; Image density; DISEASE;

D O I：

10.1016/j.anaerobe.2017.10.011

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Relationship between clinical severities of periodontal disease and the expression of the associated pathogens serve as good indicators of real time disease activity and progression. A double blind study using Image J software carried out to assess the density of the amplified band for Porphyromonas gingivalis in periodontally healthy and disease subjects. Results on image densities of P. gingivalis showed a statistical significance (p < 0.005) between healthy and diseased subjects and also within the various groups of periodontal disease severity. Thus, assessment of relative gel image density can be a simple yet valuable tool to monitor real time periodontal disease activity. (C) 2017 Elsevier Ltd. All rights reserved.

引用

页码：1 / 4

页数：4

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