LRRK2 G2385R and LRRK2 R1628P increase risk of Parkinson's disease in a Han Chinese population from Southern Mainland China

被引：25

作者：

Fu, Xiaoli ^{[1
]}

Zheng, Yifan ^{[1
]}

Hong, Hua ^{[1
]}

He, Yuemei ^{[1
]}

Zhou, Shencun ^{[1
]}

Guo, Caifeng ^{[1
]}

Liu, Yanmei ^{[1
]}

Xian, Wenbiao ^{[1
]}

Zeng, Jinsheng ^{[1
]}

Li, Jinru ^{[1
]}

Liu, Zhuolin ^{[1
]}

Chen, Ling ^{[1
]}

Pei, Zhong ^{[1
]}

机构：

[1] Sun Yat Sen Univ, Affiliated Hosp 1, Dept Neurol, Guangzhou 510080, Guangdong, Peoples R China

来源：

PARKINSONISM & RELATED DISORDERS | 2013年 / 19卷 / 03期

关键词：

Parkinson's disease; LRRK2; G2385R; LRRIQ R1628P; Genotype; Phenotype;

D O I：

10.1016/j.parkreldis.2012.08.007

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

引用

页码：397 / 398

页数：2

共 5 条

[1] WHAT FEATURES IMPROVE THE ACCURACY OF CLINICAL-DIAGNOSIS IN PARKINSONS-DISEASE - A CLINICOPATHOLOGICAL STUDY [J].

HUGHES, AJ ;

BENSHLOMO, Y ;

DANIEL, SE ;

LEES, AJ .

NEUROLOGY, 1992, 42 (06) :1142-1146

[2] Genetic analysis of LRRK2 A419V variant in ethnic Chinese [J].

Li, Nan-Nan ;

Tan, Eng-King ;

Chang, Xue-Li ;

Mao, Xue-Ye ;

Zhang, Jin-Hong ;

Zhao, Dong-Mei ;

Liao, Qiao ;

Peng, Rong .

NEUROBIOLOGY OF AGING, 2012, 33 (08) :1849.e1-1849.e3

[3]

Ross OA, 2011, LANCET NEUROL, V10, P898, DOI 10.1016/S1474-4422(11)70175-2

[4] Pathogenic mutations in Parkinson disease [J].

Tan, Eng-King ;

Skipper, Lisa M. .

HUMAN MUTATION, 2007, 28 (07) :641-653

[5] LRRK2 A419V Is Not Associated with Parkinson's Disease in Different Chinese Populations [J].

Wu, Yih Ru ;

Tan, Louis C. ;

Fu, Xiaoli ;

Chen, Chiung Mei ;

Au, Wing Lok ;

Chen, Ling ;

Chen, Yi Chun ;

Prakash, Kumar M. ;

Zheng, Yifan ;

Lee-Chen, Guey-Jen ;

Zhao, Yi ;

Zeng, Jin-Sheng ;

Tan, Eng King ;

Pei, Zhong .

PLOS ONE, 2012, 7 (07)

← 1 →