Tetrabutylammonium hexatungstate [TBA]2[W6O19]: Novel and reusable heterogeneous catalyst for rapid solvent-free synthesis of polyhydroquinolines via unsymmetrical Hantzsch reaction

被引：75

作者：

Davoodnia, Abolghasem ^{[1
]}

Khashi, Maryam ^{[1
]}

Tavakoli-Hoseini, Niloofar ^{[1
]}

机构：

[1] Islamic Azad Univ, Mashhad Branch, Dept Chem, Mashhad, Iran

来源：

CHINESE JOURNAL OF CATALYSIS | 2013年 / 34卷 / 06期

关键词：

Heterogeneous catalysis; Polyhydroquinolines; Tetrabutylammonium hexatungstate; ONE-POT SYNTHESIS; SUPPORTED POLYPHOSPHORIC ACID; MULTICOMPONENT REACTIONS; SOLID ACID; TRANSFER HYDROGENATION; BIGINELLI REACTION; EFFICIENT METHOD; FACILE SYNTHESIS; ONE-STEP; DERIVATIVES;

D O I：

10.1016/S1872-2067(12)60547-6

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A novel, efficient, and environmentally friendly method for the synthesis of polyhydroquinoline derivatives by a one-pot, four-component unsymmetrical Hantzsch condensation of dimedone, aldehydes, ethyl acetoacetate, and ammonium acetate in the presence of a catalytic amount of tetrabutylammonium hexatungstate [TBA](2)[W6O19] under solvent-free conditions has been developed. The results showed that this heterogeneous catalyst has high catalytic activity and the desired products were obtained in good to high yields. Moreover, the catalyst was found to be reusable and considerable catalytic activity was still achieved after the fifth run. (c) 2013, Dalian Institute of Chemical Physics, Chinese Academy of Sciences. Published by Elsevier B.V. All rights reserved.

引用

页码：1173 / 1178

页数：6

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