Mitochondria-targeted antioxidant therapy with MitoQ ameliorates age-related vascular endothelial dysfunction

被引:0
|
作者
Gioscia-Ryan, Rachel Anna [1 ]
LaRocca, Thomas J. [1 ]
Zigler, Melanie C. [1 ]
Murphy, Michael P. [2 ]
Seals, Douglas R. [1 ]
机构
[1] Univ Colorado, Boulder, CO 80309 USA
[2] Univ Cambridge, MRC Mitochondrial Biol Unit, Cambridge, England
来源
FASEB JOURNAL | 2013年 / 27卷
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
1125.10
引用
收藏
页数:1
相关论文
共 50 条
  • [41] Selpercatinib combination with the mitochondria-targeted antioxidant MitoQ effectively suppresses RET-mutant thyroid cancer
    Chen, Wenjing
    Dream, Sophie
    Leung, Pui-Yin
    Wu, Pui-Kei
    Wong, Stuart
    Park, Jong-In
    NPJ PRECISION ONCOLOGY, 2024, 8 (01)
  • [42] Mitochondrial-targeted antioxidant supplementation for improving age-related vascular dysfunction in humans: A study protocol
    Murray, Kevin O.
    Berryman-Maciel, Morgan
    Darvish, Sanna
    Coppock, McKinley E.
    You, Zhiying
    Chonchol, Michel
    Seals, Douglas R.
    Rossman, Matthew J.
    FRONTIERS IN PHYSIOLOGY, 2022, 13
  • [43] The mitochondria-targeted antioxidant MitoQ protects against organ damage in a lipopolysaccharide-peptidoglycan model of sepsis
    Lowes, Damon A.
    Thottakam, Bensita M. V.
    Webster, Nigel R.
    Murphy, Michael P.
    Galley, Helen F.
    FREE RADICAL BIOLOGY AND MEDICINE, 2008, 45 (11) : 1559 - 1565
  • [44] The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM+/-/ApoE-/- mice
    Mercer, John R.
    Yu, Emma
    Figg, Nichola
    Cheng, Kian-Kai
    Prime, Tracy A.
    Griffin, Julian L.
    Masoodi, Mojgan
    Vidal-Puig, Antonio
    Murphy, Michael P.
    Bennett, Martin R.
    FREE RADICAL BIOLOGY AND MEDICINE, 2012, 52 (05) : 841 - 849
  • [45] Transport and metabolism of MitoQ10, a mitochondria-targeted antioxidant, in Caco-2 cell monolayers
    Li, Yan
    Fawcett, Paul
    Zhang, Hu
    Tucker, Ian G.
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 2007, 59 (04) : 503 - 511
  • [46] Mitochondria-targeted antioxidant MitoQ protects gramicidin channels from photodynamic inactivation in planar phospholipid bilayers
    Pashkovskaya, A. A.
    Kotova, E. A.
    Chernyak, B. V.
    Antonenko, Y. N.
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 2006, : 431 - 431
  • [47] Prevention of diabetic nephropathy in Ins2+/-AkitaJ mice by the mitochondria-targeted therapy MitoQ
    Chacko, Balu K.
    Reily, Colin
    Srivastava, Anup
    Johnson, Michelle S.
    Ye, Yaozu
    Ulasova, Elena
    Agarwal, Anupam
    Zinn, Kurt R.
    Murphy, Michael P.
    Kalyanaraman, Balaraman
    Darley-Usmar, Victor
    BIOCHEMICAL JOURNAL, 2010, 432 : 9 - 19
  • [48] Oxidative Stress and Endothelial Dysfunction in Cardiovascular Disease: Mitochondria-Targeted Therapeutics
    Rocha, M.
    Apostolova, N.
    Hernandez-Mijares, A.
    Herance, R.
    Victor, V. M.
    CURRENT MEDICINAL CHEMISTRY, 2010, 17 (32) : 3827 - 3841
  • [49] Endothelial dysfunction in human arterioles following exposure to primary amyloid light chain is improved by mitochondria-targeted antioxidant
    Migrino, Raymond Q.
    Bright, Megan
    Hari, Parameswaran
    Wang, Jingli
    Kalyanaraman, Balaraman
    Gutterman, David D.
    Connors, Lawreen
    Phillips, Shane A.
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2008, 51 (10) : A280 - A280
  • [50] MITOCHONDRIA-TARGETED ANTIOXIDANT SKQR1 PEVENTS ENDOTHELIAL DYSFUNCTION DURING ISCHEMIC ACUTE KIDNEY INJURY
    Jankauskas, Stanislovas S.
    Matsievsky, Dmitry D.
    Andrianova, Nadezhda V.
    Savchenko, Elena S.
    Alieva, Irina B.
    Plotnikov, Egor Y.
    Zorov, Dmitry B.
    NEPHROLOGY DIALYSIS TRANSPLANTATION, 2016, 31 : 143 - 143