Mitochondria-targeted antioxidant therapy with MitoQ ameliorates age-related vascular endothelial dysfunction

被引:0
|
作者
Gioscia-Ryan, Rachel Anna [1 ]
LaRocca, Thomas J. [1 ]
Zigler, Melanie C. [1 ]
Murphy, Michael P. [2 ]
Seals, Douglas R. [1 ]
机构
[1] Univ Colorado, Boulder, CO 80309 USA
[2] Univ Cambridge, MRC Mitochondrial Biol Unit, Cambridge, England
来源
FASEB JOURNAL | 2013年 / 27卷
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
1125.10
引用
收藏
页数:1
相关论文
共 50 条
  • [1] Mitochondria-targeted antioxidant (MitoQ) ameliorates age-related arterial endothelial dysfunction in mice
    Gioscia-Ryan, Rachel A.
    LaRocca, Thomas J.
    Sindler, Amy L.
    Zigler, Melanie C.
    Murphy, Michael P.
    Seals, Douglas R.
    JOURNAL OF PHYSIOLOGY-LONDON, 2014, 592 (12): : 2549 - 2561
  • [2] Mitochondria-targeted antioxidant therapy with MitoQ ameliorates aortic stiffening in old mice
    Gioscia-Ryan, Rachel A.
    Battson, Micah L.
    Cuevas, Lauren M.
    Eng, Jason S.
    Murphy, Michael P.
    Seals, Douglas R.
    JOURNAL OF APPLIED PHYSIOLOGY, 2018, 124 (05) : 1194 - 1202
  • [3] Mitochondria-Targeted Antioxidant (MitoQ) and Nontargeted Antioxidant (Idebenone) Mitigate Mitochondrial Dysfunction in Corneal Endothelial Cells
    Boehm, Myriam
    Parekh, Mohit
    Deshpande, Neha
    Cheung, Queenie
    Shatz, Nathan
    Kumar, Varun
    Jurkunas, Ula V.
    CORNEA, 2025, 44 (04) : 492 - 503
  • [4] The mitochondria-targeted antioxidant improves age-related cardiac damage
    Owada, Takashi
    Saitoh, Shu-ichi
    Yamauchi, Hiroyuki
    Takeishi, Yasuchika
    FASEB JOURNAL, 2015, 29
  • [5] Drug evaluation: MitoQ - a mitochondria-targeted antioxidant
    Tauskela, Joseph S.
    IDRUGS, 2007, 10 (06) : 399 - 412
  • [6] Rescue of the Developmental Programming of Cardiovascular Dysfunction with the Mitochondria-Targeted Antioxidant MitoQ.
    Spiroski, A. M.
    Niu, Y.
    Skeffington, K. L.
    Murphy, M. P.
    Giussani, D. A.
    REPRODUCTIVE SCIENCES, 2017, 24 : 260A - 260A
  • [7] The mitochondria-targeted antioxidant MitoQ ameliorates renal ischemia reperfusion injury in a murine model
    Dare, A. J.
    Prime, T. A.
    Logan, A.
    Bolton, E. A.
    Bradley, J. A.
    Saeb-Parsy, K.
    Murphy, M. P.
    BRITISH JOURNAL OF SURGERY, 2012, 99 : 26 - 26
  • [8] Pro- and antioxidant properties of mitochondria-targeted antioxidant mitoQ
    Izyumov, D. S.
    Mostovenko, E. V.
    Korotetskaya, M. V.
    Chernyak, B. V.
    FEBS JOURNAL, 2007, 274 : 145 - 145
  • [9] Animal and human studies with the mitochondria-targeted antioxidant MitoQ
    Smith, Robin A. J.
    Murphy, Michael P.
    MITOCHONDRIAL RESEARCH IN TRANSLATIONAL MEDICINE, 2010, 1201 : 96 - 103
  • [10] Mitochondria-targeted antioxidant MitoQ ameliorates ischaemia-reperfusion injury in kidney transplantation models
    Hamed, M.
    Logan, A.
    Gruszczyk, A., V
    Beach, T. E.
    James, A. M.
    Dare, A. J.
    Barlow, A.
    Martin, J.
    Georgakopoulos, N.
    Gane, A. M.
    Crick, K.
    Fouto, D.
    Fear, C.
    Thiru, S.
    Dolezalova, N.
    Ferdinand, J. R.
    Clatworthy, M. R.
    Hosgood, S. A.
    Nicholson, M. L.
    Murphy, M. P.
    Saeb-Parsy, K.
    BRITISH JOURNAL OF SURGERY, 2021, 108 (09) : 1072 - 1081