Treatment of advanced hepatocellular carcinoma: beyond sorafenib

被引：18
作者：
Meyer, Tim [1 ]
机构：
[1] UCL, UCL Canc Inst, London WC1E 6BT, England
来源：
LANCET GASTROENTEROLOGY & HEPATOLOGY | 2018年 / 3卷 / 04期
关键词：
DOUBLE-BLIND; PHASE-3; TRIAL;
D O I：
10.1016/S2468-1253(17)30255-8
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：218 / 220
页数：4
相关论文
共 12 条
[1]  
Abou-Alfa GK, 2018, P AM SOC CLIN ON S4S, V36
[2]   Regorafenib for patients with hepatocellular carcinoma who progressed on sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled, phase 3 trial [J].
Bruix, Jordi ;
Qin, Shukui ;
Merle, Philippe ;
Granito, Alessandro ;
Huang, Yi-Hsiang ;
Bodoky, Gyrogy ;
Pracht, Marc ;
Yokosuka, Osamu ;
Rosmorduc, Olivier ;
Breder, Valeriy ;
Gerolami, Rene ;
Masi, Gianluca ;
Ross, Paul J. ;
Song, Tianqiang ;
Bronowicki, Jean-Pierre ;
Ollivier-Hourmand, Isabelle ;
Kudo, Masatoshi ;
Cheng, Ann-Lii ;
Llovet, Josep M. ;
Finn, Richard S. ;
LeBerre, Marie-Aude ;
Baumhauer, Annette ;
Meinhardt, Gerold ;
Han, Guohong .
LANCET, 2017, 389 (10064) :56-66
[3]   Adjuvant sorafenib for hepatocellular carcinoma after resection or ablation (STORM): a phase 3, randomised, double-blind, placebo-controlled trial [J].
Bruix, Jordi ;
Takayama, Tadatoshi ;
Mazzaferro, Vincenzo ;
Chau, Gar-Yang ;
Yang, Jiamei ;
Kudo, Masatoshi ;
Cai, Jianqiang ;
Poon, Ronnie T. ;
Han, Kwang-Hyub ;
Tak, Won Young ;
Lee, Han Chu ;
Song, Tianqiang ;
Roayaie, Sasan ;
Bolondi, Luigi ;
Lee, Kwan Sik ;
Makuuchi, Masatoshi ;
Souza, Fabricio ;
Le Berre, Marie-Aude ;
Meinhardt, Gerold ;
Llovet, Josep M. .
LANCET ONCOLOGY, 2015, 16 (13) :1344-1354
[4]   Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial [J].
Cheng, Ann-Lii ;
Kang, Yoon-Koo ;
Chen, Zhendong ;
Tsao, Chao-Jung ;
Qin, Shukui ;
Kim, Jun Suk ;
Luo, Rongcheng ;
Feng, Jifeng ;
Ye, Shenglong ;
Yang, Tsai-Sheng ;
Xu, Jianming ;
Sun, Yan ;
Liang, Houjie ;
Liu, Jiwei ;
Wang, Jiejun ;
Tak, Won Young ;
Pan, Hongming ;
Burock, Karin ;
Zou, Jessie ;
Voliotis, Dimitris ;
Guan, Zhongzhen .
LANCET ONCOLOGY, 2009, 10 (01) :25-34
[5]   Nivolumab (nivo) in sorafenib (sor)-naive and -experienced pts with advanced hepatocellular carcinoma (HCC): CheckMate 040 study. [J].
Crocenzi, Todd S. ;
El-Khoueiry, Anthony B. ;
Yau, Thomas Cheung ;
Melero, Ignacio ;
Sangro, Bruno ;
Kudo, Masatoshi ;
Hsu, Chiun ;
Trojan, Jorg ;
Kim, Tae -You ;
Choo, Su -Pin ;
Meyer, Tim ;
Kang, Yoon-Koo ;
Yeo, Winnie ;
Chopra, Akhil ;
Baakili, Adyb ;
Dela Cruz, Christine Marie ;
Lang, Lixin ;
Neely, Jaclyn ;
Welling, Theodore .
JOURNAL OF CLINICAL ONCOLOGY, 2017, 35
[6]   Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial [J].
El-Khoueiry, Anthony B. ;
Sangro, Bruno ;
Yau, Thomas ;
Crocenzi, Todd S. ;
Kudo, Masatoshi ;
Hsu, Chiun ;
Kim, Tae-You ;
Choo, Su-Pin ;
Trojan, Jorg ;
Welling, Theodore H., III ;
Meyer, Tim ;
Kang, Yoon-Koo ;
Yeo, Winnie ;
Chopra, Akhil ;
Anderson, Jeffrey ;
dela Cruz, Christine ;
Lang, Lixin ;
Neely, Jaclyn ;
Tang, Hao ;
Dastani, Homa B. ;
Melero, Ignacio .
LANCET, 2017, 389 (10088) :2492-2502
[7]   Outcomes with sorafenib (SOR) followed by regorafenib (REG) or placebo (PBO) for hepatocellular carcinoma (HCC): Results of the international, randomized phase 3 RESORCE trial. [J].
Finn, Richard S. ;
Merle, Philippe ;
Granito, Alessandro ;
Huang, Yi-Hsiang ;
Bodoky, Gyorgy ;
Pracht, Marc ;
Yokosuka, Osamu ;
Rosmorduc, Olivier ;
Gerolami, Rene ;
Caparello, Chiara ;
Cabrera, Roniel ;
Chang, Charissa ;
Sun, Weijing ;
Han, Guohong ;
Le Berre, Marie-Aude ;
Baumhauer, Annette ;
Meinhardt, Gerold ;
Bruix, Jordi .
JOURNAL OF CLINICAL ONCOLOGY, 2017, 35 (04)
[8]   Phase 2 study of lenvatinib in patients with advanced hepatocellular carcinoma [J].
Ikeda, Kenji ;
Kudo, Masatoshi ;
Kawazoe, Seiji ;
Osaki, Yukio ;
Ikeda, Masafumi ;
Okusaka, Takuji ;
Tamai, Toshiyuki ;
Suzuki, Takuya ;
Hisai, Takashi ;
Hayato, Seiichi ;
Okita, Kiwamu ;
Kumada, Hiromitsu .
JOURNAL OF GASTROENTEROLOGY, 2017, 52 (04) :512-519
[9]  
Kudo M, 2018, LANCET
[10]   Sorafenib in advanced hepatocellular carcinoma [J].
Llovet, Josep M. ;
Ricci, Sergio ;
Mazzaferro, Vincenzo ;
Hilgard, Philip ;
Gane, Edward ;
Blanc, Jean-Frederic ;
Cosme de Oliveira, Andre ;
Santoro, Armando ;
Raoul, Jean-Luc ;
Forner, Alejandro ;
Schwartz, Myron ;
Porta, Camillo ;
Zeuzem, Stefan ;
Bolondi, Luigi ;
Greten, Tim F. ;
Galle, Peter R. ;
Seitz, Jean-Francois ;
Borbath, Ivan ;
Haussinger, Dieter ;
Giannaris, Tom ;
Shan, Minghua ;
Moscovici, Marius ;
Voliotis, Dimitris ;
Bruix, Jordi .
NEW ENGLAND JOURNAL OF MEDICINE, 2008, 359 (04) :378-390
12