Novel Antihypertensive Therapies: Renal Sympathetic Nerve Ablation and Carotid Baroreceptor Stimulation

被引：7

作者：

Grassi, Guido ^{[1
,2
,3
]}

Seravalle, Gino ^{[2
]}

Brambilla, Gianmaria ^{[2
]}

Bombelli, Michele ^{[2
]}

Dell'Oro, Raffaella ^{[2
]}

Gronda, Edoardo ^{[3
]}

Mancia, Giuseppe ^{[2
]}

机构：

[1] Univ Milano Bicocca, San Gerardo Hosp, Med Clin, I-20052 Monza, MI, Italy

[2] Univ Milano Bicocca, Dept Clin Med & Prevent, Med Clin, I-20052 Monza, MI, Italy

[3] Ist Ric & Cura Carattere Sci Multimed, Milan, Italy

来源：

CURRENT HYPERTENSION REPORTS | 2012年 / 14卷 / 06期

关键词：

Hypertension; Blood pressure; Resistant hypertension; Interventions; Renal denervation; Carotid baroreceptor stimulation; End-organ damage; Insulin; Side effects; BAROREFLEX ACTIVATION THERAPY; RESISTANT HYPERTENSION; BLOOD-PRESSURE; DOUBLE-BLIND; DENERVATION; SPIRONOLACTONE;

D O I：

10.1007/s11906-012-0312-5

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Therapeutic interventions aimed at reducing high blood pressure still encompass a number of difficulties and limitations. This is the case particularly in resistant hypertension, i.e. a condition characterized by a very high cardiovascular risk. Carotid baroreceptor stimulation and renal sympathetic nerves ablation represent new approaches in the treatment of this condition. This paper will provide a comparison of the effects of the two procedures, highlighting their effects on blood pressure, metabolic profile, target organ damage, safety and tolerability profile.

引用

页码：567 / 572

页数：6

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