A novel copper-catalyzed reductive coupling of N-tosylhydrazones with H-phosphorus oxides

被引：63

作者：

Wu, Lei ^{[1
,2
]}

Zhang, Xiao ^{[2
]}

Chen, Qing-Qing ^{[2
]}

Zhou, An-Kun ^{[2
]}

机构：

[1] Nanjing Agr Univ, Coll Sci, Dept Chem, Nanjing 210095, Jiangsu, Peoples R China

[2] Harbin Inst Technol, Acad Fundamental & Interdisciplinary Sci, Harbin 150080, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2012年 / 10卷 / 39期

基金：

中国国家自然科学基金;

关键词：

STABILIZED PALLADIUM NANOPARTICLES; DIPHENYLPHOSPHINE OXIDE; RECYCLABLE CATALYST; DIAZO-COMPOUNDS; BOND FORMATION; HYDROPHOSPHORYLATION; NICKEL; REAGENTS; ALCOHOLS; ALKYNES;

D O I：

10.1039/c2ob26414e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report here a novel C(sp(3))-P bonds formation via copper-catalyzed reductive coupling of N-tosylhydrazones with H-phosphorus oxides. A variety of aliphatic and aromatic substrates bearing electron-rich and electron-deficient substituents affords phosphine oxide derivatives with moderate to good yields. This work suggests a new transformation of aldehydes/ketones via N-tosylhydrazones to organophosphorus compounds.

引用

页码：7859 / 7862

页数：4

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