Some Thermodynamic Characteristics of Paracetamol Dispersing with the SEDS Method

被引:1
作者
Khabriev, I. Sh. [1 ]
Khairutdinov, V. F. [1 ]
Zaripov, Z. I. [1 ]
Gumerov, F. M. [1 ]
Petrov, V. A. [1 ]
Kuznetsova, N. V. [1 ]
Khuzakhanov, R. M. [1 ]
机构
[1] Kazan Natl Res Technol Univ, Kazan, Russia
关键词
paracetamol; supercritical CO2; phase equilibrium; solubility; heat capacity; dispersing with the SEDS method; SUPERCRITICAL CARBON-DIOXIDE; POLYMER PARTICLES; SOLUBILITY; ACETAMINOPHEN; POLYMORPHISM; ACETONE; CRYSTALLIZATION; TEMPERATURES; EQUILIBRIUM; CALORIMETRY;
D O I
10.1134/S199079311708005X
中图分类号
O64 [物理化学(理论化学)、化学物理学]; O56 [分子物理学、原子物理学];
学科分类号
070203 ; 070304 ; 081704 ; 1406 ;
摘要
The solubility of paracetamol in supercritical carbon dioxide and its mixtures with acetone is experientially studied. The isobaric heat capacity of paracetamol and the systems "paracetamol-CO2" and "paracetamol-acetone-CO2" is measured under pressures 7-29 MPa and temperatures 303-523 K. The results of paracetamol dispersing using the SEDS method (Solution Enhanced Dispersion by Supercritical Fluids) are presented.
引用
收藏
页码:1231 / 1245
页数:15
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