Surface enhanced Raman scattering for multiplexed detection

被引：107

作者：

Dougan, Jennifer A. ^{[1
]}

Faulds, Karen ^{[1
]}

机构：

[1] Univ Strathclyde, Dept Pure & Appl Chem, WestCHEM, Glasgow G1 1XL, Lanark, Scotland

来源：

ANALYST | 2012年 / 137卷 / 03期

基金：

英国工程与自然科学研究理事会;

关键词：

LABELED DNA; SERRS DYES; AZO DYES; OLIGONUCLEOTIDES; PROBE; SPECTROSCOPY; PYRIDINE; SPECTRA; ACID;

D O I：

10.1039/c2an15979a

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The multiplexed detection of biological analytes from complex mixtures is of crucial importance for the future of intelligent management and detection of disease. This review focuses on recent advances in the use of surface enhanced Raman scattering (SERS) spectroscopy as an analytical technique that can deliver multiplexed detection for a variety of biological target in increasingly complex media. The use of SERS has developed from the multipelxed detection of custom dye molecules to biomolecules such as DNA and proteins. Recent work has also shown the capability of SERS multiplexing for in vivo as well as in vitro applications.

引用

页码：545 / 554

页数：10

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