COVID-19 and Inborn Errors of Immunity

被引：23
作者：
Delmonte, Ottavia M. [1 ]
Castagnoli, Riccardo [1 ,2 ,3 ]
Notarangelo, Luigi D. [1 ]
机构：
[1] NIAID, Lab Clin Immunol & Microbiol, NIH, 9000 Rockville Pike, Bethesda, MD 20892 USA
[2] Univ Pavia, Dept Clin Surg Diagnost & Pediat Sci, Pavia, Italy
[3] Fdn Ist Ricovero Cura Carattere Sci Policlin San, Pediat Clin, Pavia, Italy
来源：
PHYSIOLOGY | 2022年 / 37卷 / 06期
基金：
美国国家卫生研究院;
关键词：
COVID-19; vaccine; inborn errors of immunity; primary immune deficiency; SARS-COV-2; CORONAVIRUS DISEASE 2019; COMMON VARIABLE IMMUNODEFICIENCY; MULTISYSTEM INFLAMMATORY SYNDROME; X-LINKED AGAMMAGLOBULINEMIA; SARS-COV-2; PATIENT; CHILDREN; INDIVIDUALS; VACCINATION;
D O I：
10.1152/physiol.00016.2022
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
Inborn errors of immunity (IEI) are a heterogeneous group of disorders affecting immune host defense and immunoregulation. Considering the predisposition to develop severe and chronic infections, it is crucial to understand the clinical evolution of COVID-19 in IEI patients. This review analyzes clinical outcomes following SARS-CoV-2 infection, as well as response to COVID-19 vaccines in patients with IEI.
引用
收藏
页码：290 / 301
页数：12
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